Protein Alignment Syn and syn1

DIOPT Version :10

• Sequence 1: NP_731459.2
• Gene: Syn / 41247
• FlyBaseID: FBgn0004575
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_001119909.1
• Gene: syn1 / 570672
• ZFINID: ZDB-GENE-081105-93
• Length: 670
• Species: Danio rerio
• Alignment Length: 811
• Identity: 258/811 - (31%)
• Similarity: 365/811 - (45%)
• Gaps: 178/811 - (21%)

  Fly    14 VNFLKRRFSSGDLSSEVDDVDPNS-LPPAARPIQDQPTKPPVAGGPPNMPPPPAPGQPAGAAPEL 77
            :|:|:||.|..:..|.:    ||. :....||...|.:..||..........|||.|..||....
Zfish     1 MNYLRRRLSDSNFMSNL----PNGYMGDLQRPDPPQQSPAPVLSPGSQERRQPAPSQSTGAGFFS 61

  Fly    78 SLSFGAGKTPATAAPAPPRGVSAPTSPAKSRESLLQRVQSLTGAARDQGASILGAAVQSATQRAP 142
            |:|....:|.|.||                                        |....||:|..
Zfish    62 SISNAVKQTTAAAA----------------------------------------ATFNEATERGI 86

  Fly   143 AFSKDKYFTLLVLDDQNTDWSKYFRGRRLHGDFDIRVEQAEFRDITVVSSADTGPVVTMAAYRSG 207
            .....|  .|||:|||.|||:|.|:|:::|||.||:||||:|.::.:|:.|.....|.:.|.|||
Zfish    87 GSGNAK--ILLVIDDQQTDWAKVFKGKKVHGDCDIKVEQADFSEVNLVAHATGSYSVDIEAIRSG 149

  Fly   208 TRVARSFRPDFVLIRQ----PPRDGSSDYRSTILGLKYGGVPSINSLHSIYQFQDKPWVFSHLLQ 268
            .::.:..:|||||:||    ..::|  |:|:.::||:|.|:||:|||||:|.|.|||||||.|.:
Zfish   150 NKITKCIKPDFVLVRQHAFSMAKNG--DHRNIVIGLQYAGLPSVNSLHSVYNFCDKPWVFSQLSR 212

  Fly   269 LQRRLGRDGFPLIEQTFFPNPRDLFQFTKFPSVLKAGHCHGGVATARLENQSALQDAAGLVSGAG 333
            |.::||.:.||||:|.::||.:::.....||.|:|.||.|.|:...:::||...||.|.:|:
Zfish   213 LYKQLGPEEFPLIDQVYYPNHKEMITTPGFPVVVKMGHAHSGMGKVKVDNQYDFQDIASVVA--- 274

  Fly   334 NDSHCYCTIEPYIDAKFSVHIQKIGNNYKAFMRKSITGNWKTNQGSAMLEQITLTEKYKSWVDEI 398
             .:..|.|.||:||||:.:.|||||.||||:||.||:||||||.|||||||:.::::|:.|||..
Zfish   275 -LTKTYATSEPFIDAKYDIRIQKIGENYKAYMRTSISGNWKTNTGSAMLEQVAMSDRYRMWVDVC 338

  Fly   399 SELFGGMEVCGLSVVVAKDGREYIISACDSTFALIGDTQEEDRRQIADLVSGRM-QNVCRPSMAQ 462
            ||:|||:::|.:..:..||||:|||.....:..||||.|:|||..:||||..:| :.|.|.|...
Zfish   339 SEVFGGLDICAVEALHGKDGRDYIIEVVGCSMPLIGDQQDEDRALMADLVVAKMNETVPRTSAPT 403

  Fly   463 T----GPGKLP---SRSSVSSRAESPTDEG---------VAPTPPLPAGPRPAPMGGPPPIPERT 511
            |    ||...|   |:|.|....:.|..:|         .|.....|...||:|.|.||
Zfish   404 TVRSQGPAVSPQPISQSRVPQAQQRPPPQGGPQQAAASTAATRQGAPPQQRPSPQGQPP------ 462

  Fly   512 SPAVGSIGRLSSRSSISEVPEEPSSSGPSTVGGVRRDSQTSQSSTISSSVSRAGQRPPQTQNSVV 576
                     ..|:|..|.:.:.|.:..|       |.:|..|..  :|..|.|.||||..|
Zfish   463 ---------AQSQSVTSPIAQNPPAQQP-------RPNQPPQRQ--ASQGSAAPQRPPAAQ---- 505

  Fly   577 EDAEDTMKNLRKTFAGIFGDMXEIANKKRGRTASETSSGSGPGSVPSSAGPGSGFSSSFLGKQFS 641
                                    ...:||...|:...|      |...||.:|      |:...
Zfish   506 ------------------------IPAQRGSPQSQRQGG------PQQGGPQTG------GQSPK 534

  Fly   642 FAGKGEGVISTQPTQRPSEEPPAIPTTASSAVRPESSVSV------SDSRNTDTLTERAGA---- 696
            .||        ||.|||.:.....||...:...|:.:...      ...|...|...|..|
Zfish   535 PAG--------QPQQRPQQPRQGQPTRQPTQGGPQQTQDAPQPAPQGSPRPPTTQQPRPTAPGQG 591

  Fly   697 ---GYQPVTNYEQQERVNPFDKEPSKSGSAASIHTSSSSSISSSSISSRINRNGNAIQSPPPPAG 758
               |.:|....:.|....|....|:.|||.   ..:.|.|::            |....|..||.
Zfish   592 GPGGTRPPLQQKPQPPQKPSPDHPALSGSP---QLNKSQSLT------------NTFNIPETPAA 641

  Fly   759 PPPPPPTNVTAVGSNANSSSGYRNSFSSSLS 789
            ....|..:    .:.|.:....|.||:|..|
Zfish   642 QHQSPSQD----EAKAETIRNLRKSFASLFS 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syn	NP_731459.2	Synapsin	150..246	CDD:460438	43/99 (43%)
		CPSase_L_D2	248..452	CDD:473076	102/203 (50%)
		PHA03307	425..>700	CDD:223039	73/304 (24%)
syn1	NP_001119909.1	Synapsin_N	1..32	CDD:463155	10/34 (29%)
		Synapsin	92..190	CDD:460438	44/101 (44%)
		CPSase_L_D2	192..394	CDD:473076	103/205 (50%)
		PHA03247	<397..595	CDD:223021	58/269 (22%)