Protein Alignment Syn and Syn

DIOPT Version :10

• Sequence 1: NP_731459.2
• Gene: Syn / 41247
• FlyBaseID: FBgn0004575
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: XP_061504187.1
• Gene: Syn / 4577141
• VectorBaseID: AGAMI1_013507
• Length: 553
• Species: Anopheles gambiae
• Alignment Length: 570
• Identity: 394/570 - (69%)
• Similarity: 455/570 - (79%)
• Gaps: 47/570 - (8%)

  Fly    56 GGPPNMPPPPAPGQ----------PAGAA-----PELSLSFGAGKTPATAAPAPPRGVSAPTSPA 105
            |||||:|||||||.          |.|:|     ||||||||.|       || .||.|||:|||
Mosquito     3 GGPPNIPPPPAPGTAGSVSPGGPVPPGSAPPTGGPELSLSFGKG-------PA-QRGTSAPSSPA 59

  Fly   106 KSRESLLQRVQSLTGAARDQGASILGAAVQSATQRAPAFSKDKYFTLLVLDDQNTDWSKYFRGRR 170
            ||||||||||||||||||||||||:||||.:|::..| |::||.|||||:|||||||||||||:|
Mosquito    60 KSRESLLQRVQSLTGAARDQGASIIGAAVSTASRVQP-FNRDKCFTLLVVDDQNTDWSKYFRGKR 123

  Fly   171 LHGDFDIRVEQAEFRDITVVSSADTGPVVTMAAYRSGTRVARSFRPDFVLIRQPPRDGSSDYRST 235
            ||.|:||||||||||:|.:.:|||:||:|  ...|.|::.|:.|||||:|:||||||||.|||||
Mosquito   124 LHSDYDIRVEQAEFREIMLTASADSGPMV--GCNRGGSKQAKPFRPDFILVRQPPRDGSKDYRST 186

  Fly   236 ILGLKYGGVPSINSLHSIYQFQDKPWVFSHLLQLQRRLGRDGFPLIEQTFFPNPRDLFQFTKFPS 300
            :||||||||||||||||:||||||||||:||||||||||||.|||:||||||||:|:|.:|:||.
Mosquito   187 LLGLKYGGVPSINSLHSLYQFQDKPWVFAHLLQLQRRLGRDAFPLVEQTFFPNPKDMFTWTRFPC 251

  Fly   301 VLKAGHCHGGVATARLENQSALQDAAGLVSGAG-NDSHCYCTIEPYIDAKFSVHIQKIGNNYKAF 364
            ||||||||||.|||:|:|..||||||||:.|.| :|:..||::||||||||.|||||||.:||||
Mosquito   252 VLKAGHCHGGKATAKLDNPGALQDAAGLLCGTGLSDNGSYCSLEPYIDAKFDVHIQKIGTSYKAF 316

  Fly   365 MRKSITGNWKTNQGSAMLEQITLTEKYKSWVDEISELFGGMEVCGLSVVVAKDGREYIISACDST 429
            |||||:|||||||||||||||.:|||||:||||:|||||||||||::|:|:|:|:|:||||.|||
Mosquito   317 MRKSISGNWKTNQGSAMLEQIPMTEKYKTWVDEVSELFGGMEVCGVAVIVSKEGKEFIISAADST 381

  Fly   430 FALIGDTQEEDRRQIADLVSGRMQNVCRPSMAQTGPGKLPSRSSVSSRAESPTDEGVAPTPPLPA 494
            |.|:|||||||||||||||.|||||||||||..    |..||||:|||..|||::    .||:|.
Mosquito   382 FPLMGDTQEEDRRQIADLVVGRMQNVCRPSMMT----KAVSRSSISSRGTSPTED----APPVPI 438

  Fly   495 GPRPAPM-GGPPPIPERTSPAVGSIGRLSSRSSIS-EVPEEPSSSGPSTVGGVRRDSQTSQSSTI 557
            |.||.|: ||||||||||:|.||||||..|.||.| |.||:||...|:.....|||||.||||::
Mosquito   439 GTRPVPVGGGPPPIPERTTPGVGSIGRHGSFSSQSGEPPEQPSERAPTLNSVGRRDSQASQSSSV 503

  Fly   558 S--SSVSRA----GQRPPQTQN----SVVEDAEDTMKNLRKTFAGIFGDM 597
            |  ||.|.|    |:.|.....    ||||||||||||||||||||||||
Mosquito   504 SGVSSASAARSGVGKVPAAGAGPGGPSVVEDAEDTMKNLRKTFAGIFGDM 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syn	NP_731459.2	Synapsin	150..246	CDD:460438	69/95 (73%)
		CPSase_L_D2	248..452	CDD:473076	160/204 (78%)
		PHA03307	425..>700	CDD:223039	117/185 (63%)
Syn	XP_061504187.1	None