Protein Alignment Syn and syn3

DIOPT Version :10

• Sequence 1: NP_731459.2
• Gene: Syn / 41247
• FlyBaseID: FBgn0004575
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_001123797.1
• Gene: syn3 / 100170548
• XenbaseID: XB-GENE-5793907
• Length: 580
• Species: Xenopus tropicalis
• Alignment Length: 632
• Identity: 235/632 - (37%)
• Similarity: 334/632 - (52%)
• Gaps: 101/632 - (15%)

  Fly    14 VNFLKRRFSSGDLSSEVDDVDPNSLPPAARPIQDQPTKPPVAGGPPNMPPPPAPGQPAGAAPELS 78
            :|||:||.|.   ||.|.::....:....||  |..|..||
 Frog     1 MNFLRRRLSD---SSFVANLPNGYMMDLQRP--DNSTSSPV------------------------ 36

  Fly    79 LSFGAGKTPATAAPAPPRGVSAPTSPAKSRESLLQRVQSLTGAARDQGASILGAAVQSATQRAPA 143
                        :||..|....|:.||.:.........|:|.|.:....:..|...|:.....|.
 Frog    37 ------------SPALDRKQQPPSVPASASTGGTSLFSSITNAVKQTTQAAAGLVEQTGAPAPPV 89

  Fly   144 FSKDKYFTLLVLDDQNTDWSKYFRGRRLHGDFDIRVEQAEFRDITVVSSADTGPVVTMAAYRSGT 208
            ..|.|  .|||:||.:|||:|||||::::.|::||||||||.::.:.:..:.|.:|.|...|:||
 Frog    90 VLKPK--ILLVIDDPHTDWAKYFRGKKVNKDYEIRVEQAEFSELNLAAYVNGGCMVDMQVMRNGT 152

  Fly   209 RVARSFRPDFVLIRQPPRDGS--SDYRSTILGLKYGGVPSINSLHSIYQFQDKPWVFSHLLQLQR 271
            :|.:||:|||:||||.....:  .|:||.::||:||.:||:|||:|||.|..||||||.|:::.:
 Frog   153 KVVKSFKPDFLLIRQHAYSMTLGEDFRSLVIGLQYGNLPSVNSLYSIYNFCSKPWVFSQLIKIFQ 217

  Fly   272 RLGRDGFPLIEQTFFPNPRDLFQFTKFPSVLKAGHCHGGVATARLENQSALQDAAGLVSGAGNDS 336
            :||.|.|||::|:||||.:.:.....||.|:|.||.|.|:...:::||...||.|.:|:.|
 Frog   218 KLGADKFPLVDQSFFPNHKQMLTAASFPVVVKMGHAHAGMGKVKVDNQYDFQDMASVVAMA---- 278

  Fly   337 HCYCTIEPYIDAKFSVHIQKIGNNYKAFMRKSITGNWKTNQGSAMLEQITLTEKYKSWVDEISEL 401
            ..|.|.||:||:|:.:.||||||||||:||.||:||||.|.||||||||.:|::|:.|||..||:
 Frog   279 KTYVTTEPFIDSKYDIRIQKIGNNYKAYMRTSISGNWKANTGSAMLEQIAMTDRYRLWVDSCSEM 343

  Fly   402 FGGMEVCGLSVVVAKDGREYIISACDSTFALIGDTQEEDRRQIADLVSGRM-QNVCRPSMAQTGP 465
            |||:::|.:..|.:|||::|||...||:..|||:..||||..:||||..:| |:|...|.| ..|
 Frog   344 FGGLDICAVKAVHSKDGKDYIIEVMDSSMPLIGEHVEEDRHLVADLVIAKMTQHVQLTSQA-ASP 407

  Fly   466 GK-LPSRSSVSSRAESPTDEGVAPTPPLPAGPRPAPMGGP------------PPIPERTSP---- 513
            |: |.....|..:|..|..: ..|.||..|.|||||.|||            ||...|.||
 Frog   408 GRPLAMPQQVQPQAVKPQMQ-PQPGPPGTAQPRPAPQGGPRQAQGSPAQRTGPPAQPRLSPQGQQ 471

  Fly   514 ----AVGS-----------IGRLSSRSSISEVPE--EPSSSGPSTVGGVRRDS------------ 549
                ..||           :.|.:|.:...:.|:  .|..|.|...|..:...
 Frog   472 PQTSQPGSPQTQRSPNSPQLPRPASGTPTGQTPKSASPQPSRPPAQGQAQNPPGPGPTAKPQPML 536

  Fly   550 QTSQSSTISSSVSRAGQRPPQTQNSVVEDAEDTMKNLRKTFAGIFGD 596
            ..|||.|.:.::|....|...|::   |...:|::||||:||.:|.|
 Frog   537 NKSQSLTNNFNISDPSARSTGTED---EAKAETIRNLRKSFASLFSD 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syn	NP_731459.2	Synapsin	150..246	CDD:460438	45/97 (46%)
		CPSase_L_D2	248..452	CDD:473076	105/203 (52%)
		PHA03307	425..>700	CDD:223039	67/219 (31%)
syn3	NP_001123797.1	Synapsin_N	1..29	CDD:463155	11/32 (34%)
		Synapsin	94..192	CDD:460438	46/99 (46%)
		CPSase_L_D2	194..396	CDD:473076	106/205 (52%)
		PHA03247	<404..534	CDD:223021	33/131 (25%)