Protein Alignment Syn and syn3

DIOPT Version :9

• Sequence 1: NP_731459.2
• Gene: Syn / 41247
• FlyBaseID: FBgn0004575
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: NP_001123797.1
• Gene: syn3 / 100170548
• XenbaseID: XB-GENE-5793907
• Length: 580
• Species: Xenopus tropicalis
• Alignment Length: 632
• Identity: 235/632 - (37%)
• Similarity: 334/632 - (52%)
• Gaps: 101/632 - (15%)

  Fly    14 VNFLKRRFSSGDLSSEVDDVDPNSLPPAARPIQDQPTKPPVAGGPPNMPPPPAPGQPAGAAPELS 78
            :|||:||.|.   ||.|.::....:....||  |..|..||
 Frog     1 MNFLRRRLSD---SSFVANLPNGYMMDLQRP--DNSTSSPV------------------------ 36

  Fly    79 LSFGAGKTPATAAPAPPRGVSAPTSPAKSRESLLQRVQSLTGAARDQGASILGAAVQSATQRAPA 143
                        :||..|....|:.||.:.........|:|.|.:....:..|...|:.....|.
 Frog    37 ------------SPALDRKQQPPSVPASASTGGTSLFSSITNAVKQTTQAAAGLVEQTGAPAPPV 89

  Fly   144 FSKDKYFTLLVLDDQNTDWSKYFRGRRLHGDFDIRVEQAEFRDITVVSSADTGPVVTMAAYRSGT 208
            ..|.|  .|||:||.:|||:|||||::::.|::||||||||.::.:.:..:.|.:|.|...|:||
 Frog    90 VLKPK--ILLVIDDPHTDWAKYFRGKKVNKDYEIRVEQAEFSELNLAAYVNGGCMVDMQVMRNGT 152

  Fly   209 RVARSFRPDFVLIRQPPRDGS--SDYRSTILGLKYGGVPSINSLHSIYQFQDKPWVFSHLLQLQR 271
            :|.:||:|||:||||.....:  .|:||.::||:||.:||:|||:|||.|..||||||.|:::.:
 Frog   153 KVVKSFKPDFLLIRQHAYSMTLGEDFRSLVIGLQYGNLPSVNSLYSIYNFCSKPWVFSQLIKIFQ 217

  Fly   272 RLGRDGFPLIEQTFFPNPRDLFQFTKFPSVLKAGHCHGGVATARLENQSALQDAAGLVSGAGNDS 336
            :||.|.|||::|:||||.:.:.....||.|:|.||.|.|:...:::||...||.|.:|:.|
 Frog   218 KLGADKFPLVDQSFFPNHKQMLTAASFPVVVKMGHAHAGMGKVKVDNQYDFQDMASVVAMA---- 278

  Fly   337 HCYCTIEPYIDAKFSVHIQKIGNNYKAFMRKSITGNWKTNQGSAMLEQITLTEKYKSWVDEISEL 401
            ..|.|.||:||:|:.:.||||||||||:||.||:||||.|.||||||||.:|::|:.|||..||:
 Frog   279 KTYVTTEPFIDSKYDIRIQKIGNNYKAYMRTSISGNWKANTGSAMLEQIAMTDRYRLWVDSCSEM 343

  Fly   402 FGGMEVCGLSVVVAKDGREYIISACDSTFALIGDTQEEDRRQIADLVSGRM-QNVCRPSMAQTGP 465
            |||:::|.:..|.:|||::|||...||:..|||:..||||..:||||..:| |:|...|.| ..|
 Frog   344 FGGLDICAVKAVHSKDGKDYIIEVMDSSMPLIGEHVEEDRHLVADLVIAKMTQHVQLTSQA-ASP 407

  Fly   466 GK-LPSRSSVSSRAESPTDEGVAPTPPLPAGPRPAPMGGP------------PPIPERTSP---- 513
            |: |.....|..:|..|..: ..|.||..|.|||||.|||            ||...|.||
 Frog   408 GRPLAMPQQVQPQAVKPQMQ-PQPGPPGTAQPRPAPQGGPRQAQGSPAQRTGPPAQPRLSPQGQQ 471

  Fly   514 ----AVGS-----------IGRLSSRSSISEVPE--EPSSSGPSTVGGVRRDS------------ 549
                ..||           :.|.:|.:...:.|:  .|..|.|...|..:...
 Frog   472 PQTSQPGSPQTQRSPNSPQLPRPASGTPTGQTPKSASPQPSRPPAQGQAQNPPGPGPTAKPQPML 536

  Fly   550 QTSQSSTISSSVSRAGQRPPQTQNSVVEDAEDTMKNLRKTFAGIFGD 596
            ..|||.|.:.::|....|...|::   |...:|::||||:||.:|.|
 Frog   537 NKSQSLTNNFNISDPSARSTGTED---EAKAETIRNLRKSFASLFSD 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syn	NP_731459.2	Synapsin	151..246	CDD:280283	45/96 (47%)
		ATP-grasp_4	248..452	CDD:302634	105/203 (52%)
		GSK-3_bind	427..>543	CDD:283100	49/150 (33%)
syn3	NP_001123797.1	Synapsin_N	1..31	CDD:371148	12/34 (35%)
		Synapsin	95..192	CDD:366909	45/96 (47%)
		CPSase_L_D2	194..396	CDD:388419	106/205 (52%)
		PHA03247	<404..534	CDD:223021	33/131 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	238	1.000	Domainoid score	I2254
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H68320
Inparanoid	1	1.050	373	1.000	Inparanoid score	I2065
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001672
OrthoInspector	1	1.000	-	-		otm49157
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1069
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.050