Protein Alignment Syn and syn1

DIOPT Version :9

• Sequence 1: NP_731459.2
• Gene: Syn / 41247
• FlyBaseID: FBgn0004575
• Length: 1041
• Species: Drosophila melanogaster
• Sequence 2: XP_031746088.1
• Gene: syn1 / 100158514
• XenbaseID: XB-GENE-6449731
• Length: 693
• Species: Xenopus tropicalis
• Alignment Length: 837
• Identity: 277/837 - (33%)
• Similarity: 389/837 - (46%)
• Gaps: 195/837 - (23%)

  Fly    14 VNFLKRRFSSGDLSSEVDDVDPNS-LPPAARPIQDQPTKPPVAGGPPNMPPPPAPGQPAGAAPEL 77
            :|:|:||.|..:..:.:    ||. :....||  |.|..||  .||...|||||
 Frog     2 MNYLRRRLSDSNFMANL----PNGYMSDLQRP--DPPAPPP--PGPQGPPPPPA----------- 47

  Fly    78 SLSFGAGKTPATAAPAPPRGVSAPTSPAKSRESLLQRVQSLTGAARDQGASILGAAVQSATQRAP 142
                        .:|.||       |......||...|:..|.|..:|        |.:||...|
 Frog    48 ------------VSPEPP-------SSGGFFSSLSNAVKQTTAALSEQ--------VSTATGGGP 85

  Fly   143 AFSKDKYFTLLVLDDQNTDWSKYFRGRRLHGDFDIRVEQAEFRDITVVSSADTGPVVTMAAYRSG 207
            .....|  .|||:|:.:|||.|.|:|||::|::||:||||||.|:.:|:.::.|..|.:...|:|
 Frog    86 GPKGSK--LLLVIDEPHTDWGKLFKGRRINGEYDIKVEQAEFCDLNLVAHSNGGFSVDLEVMRNG 148

  Fly   208 TRVARSFRPDFVLIRQ----PPRDGSSDYRSTILGLKYGGVPSINSLHSIYQFQDKPWVFSHLLQ 268
            .:|.||.:||||||||    ..|:|  |:||.::||:|.||||:|||||:|.|.|||||||.|::
 Frog   149 VKVVRSLKPDFVLIRQHAFSMARNG--DFRSLVIGLQYAGVPSLNSLHSVYNFCDKPWVFSQLVR 211

  Fly   269 LQRRLGRDGFPLIEQTFFPNPRDLFQFTKFPSVLKAGHCHGGVATARLENQSALQDAAGLVSGAG 333
            |.|:||.|.|||||||::||.:::...:|||.|:|.||.|.|:...:::||...||.|.:|:
 Frog   212 LHRKLGPDDFPLIEQTYYPNHKEMLTASKFPVVIKMGHAHSGMGKVKVDNQYDFQDIASVVA--- 273

  Fly   334 NDSHCYCTIEPYIDAKFSVHIQKIGNNYKAFMRKSITGNWKTNQGSAMLEQITLTEKYKSWVDEI 398
             .:..|.|.||:||||:.|.|||||:||||:||.||:||||||.||||||||.::::||.|||..
 Frog   274 -LTKTYATSEPFIDAKYDVRIQKIGSNYKAYMRTSISGNWKTNTGSAMLEQIAVSDRYKLWVDAC 337

  Fly   399 SELFGGMEVCGLSVVVAKDGREYIISACDSTFALIGDTQEEDRRQIADLVSGRM-QNV-CRPSMA 461
            :::|||:::|.:..:..||||::||....|:..||||.||||::.|||||..|| ||: |.||::
 Frog   338 ADIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDQQEEDKQLIADLVVTRMSQNLQCSPSLS 402

  Fly   462 QTGPGKLPSRSSVSSRAESPTDEGVAPTPPLPAGPRPAPMGGP--PPIPERTSPAVGSIGRLSSR 524
            :...|..|....|.||:.:|..:  ....|    .||.|.|||  ..:|.|..|.
 Frog   403 RPTHGPQPQAQVVHSRSATPIQQ--QQQQP----QRPPPQGGPQAAQVPARQGPP---------- 451

  Fly   525 SSISEVPEE-PSSSGPSTVGGVRRDSQTSQSSTISSSVSRAGQRPPQTQNSVVEDAEDTMKNLRK 588
                  |:: |...|....|  .....:|....:.|..::..|.|||.|...|...:.
 Frog   452 ------PQQRPPPQGQQVQG--LSPQPSSHPQNLPSPGAQQRQIPPQQQPQQVRPPQQ------- 501

  Fly   589 TFAGIFGDMXEIANKKRGRTASETSSGSGP--------------GSVPSSAGPGSGFSSSFLGKQ 639
                        .:.::.::.....|..||              |..|....||....|
 Frog   502 ------------PSPRQSQSPQRQPSPQGPQSPQRQQQGPPMPTGPKPMGVQPGQPRQS------ 548

  Fly   640 FSFAGKGEGVISTQPTQRPSEEPPAIPTTASSAVRPESSVSVSDSRNTDTLTERAGAGYQPVTNY 704
                |.....:...|.|:|:  ||      .|...|:..:.....:....|.:|...   |....
 Frog   549 ----GPPRQAVPVGPQQKPA--PP------GSQQPPQQGIRQPMQQQQPPLQQRQSV---PGAPQ 598

  Fly   705 EQQERVNPFDKEPSKS----GSAASIHTSSSSSISSSSISSRINRNGNAIQSP----PPPAGPPP 761
            :||:...|..::|..:    |.|:|                   |.|.. |.|    .|.|..||
 Frog   599 QQQQPQRPMTQQPRPNPQGPGQASS-------------------RPGGP-QKPQVAQKPGAELPP 643

  Fly   762 PPPTNVTAVGSNANSSSGYRNSFS--------SSLSKDKTSYGNYGSTTSVETITRM 810
            |.|        ..|.|....|||:        |:||.|:         ...|||..:
 Frog   644 PQP--------QLNKSQSLTNSFTLADTAAPRSNLSHDE---------AKAETIRNL 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syn	NP_731459.2	Synapsin	151..246	CDD:280283	48/98 (49%)
		ATP-grasp_4	248..452	CDD:302634	109/203 (54%)
		GSK-3_bind	427..>543	CDD:283100	40/120 (33%)
syn1	XP_031746088.1	Synapsin_N	2..28	CDD:402285	7/29 (24%)
		Synapsin	93..189	CDD:396588	48/97 (49%)
		CPSase_L_D2	191..393	CDD:418439	111/205 (54%)
		PHA03247	<467..648	CDD:223021	44/248 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	238	1.000	Domainoid score	I2254
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	373	1.000	Inparanoid score	I2065
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001672
OrthoInspector	1	1.000	-	-		otm49157
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1069
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.050