DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12814 and cutl-24

DIOPT Version :9

Sequence 1:	NP_001262454.1	Gene:	CG12814 / 41246	FlyBaseID:	FBgn0037796	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_001023450.1	Gene:	cutl-24 / 176831	WormBaseID:	WBGene00021396	Length:	601	Species:	Caenorhabditis elegans

Alignment Length:	278	Identity:	61/278 - (21%)
Similarity:	92/278 - (33%)	Gaps:	78/278 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LLPVLLFLAGQVTTQEP--PASPS---------EFAPHVTATCKAGTMNIKVKMSSGYTGAVHVR 68
            :.||:.......|...|  |..|:         .|||....|.|....  |....|.|..|....
Worm   269 MAPVMFTFPTTTTPLMPLFPIIPNVHFKQGVGVPFAPGTLPTTKVDAS--KWNDPSAYATAPSTV 331

  Fly    69 DYRTP----------GCMAMGDGSDQVAFSLNLWAKQGA--------SDYCGILVSNVSGSNRTE 115
            |..||          ......|.|.::..:..:.|..|.        .|...:|       ..|:
Worm   332 DSTTPKTYREQPPTADAPFSSDNSKEIHETSTIVASPGVPRPQADQPKDITSVL-------KTTQ 389

  Fly   116 ERSIQLAVRVHKTLEL--ADDKFY--VITCGKSGYARDDNAHVVLKFLENDHRVRETVYGHEYKI 176
            |:.|:..|    |||:  .:..|.  |.|..|.|    ||..:|:|
Worm   390 EQQIEPEV----TLEIQRGEGPFAPPVTTPIKIG----DNISLVVK------------------- 427

  Fly   177 RAEFSKPNDTYGLRVGNCFAFDKKNRTQ-KLTDDSGCPYDSKIISRFVPTADGRAAE-----AVL 235
            ...:....|.:.:.|.:|||.|.|..|: ::.|::||....:..|   |....:.:|     .:|
Worm   428 AKSYLNETDQFDMFVHSCFATDGKGDTKVQMIDENGCVIRLEFAS---PLHRAKDSENTMFYYLL 489

  Fly   236 SSMFKFPEGSEVHLQCDV 253
            ...||||...:|:..|.:
Worm   490 IKAFKFPGPDDVYFSCTI 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12814	NP_001262454.1	ZP	45..256	CDD:214579	52/237 (22%)
CG12814	NP_001262454.1	Zona_pellucida	<181..256	CDD:278526	21/79 (27%)
cutl-24	NP_001023450.1	Zona_pellucida	34..>92	CDD:391783
		PHA03247	<169..415	CDD:223021	33/158 (21%)
		Zona_pellucida	<388..516	CDD:391783	37/150 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46560
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010