DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6254 and CG17829

DIOPT Version :9

Sequence 1:	NP_649983.2	Gene:	CG6254 / 41244	FlyBaseID:	FBgn0037794	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster

Alignment Length:	317	Identity:	77/317 - (24%)
Similarity:	123/317 - (38%)	Gaps:	59/317 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   309 DISREHVT--DEEDEISEVPAMYKCNICKKPY-KKPKAY------KRHMEE-----VHNTVADDL 359
            |..||.|:  :.:|.|.: .|:::.:|.|.|. ::||..      .:||..     .|.:...:.
  Fly   139 DCEREFVSIVEFQDHIVK-HALFEYDIQKTPEDERPKTMCNWAMCHKHMGNKYRLIEHISTHSNK 202

  Fly   360 PQLECNQCKLCFPTVAQLHAHHRTHVRAKPKTDN---CCPHCEKRFTTSGTLKRHIEGIHNQIKP 421
            .|:.|..|...|.|...|.    .|:|.:|:.:.   .|..|.|.|.|...||.|:.   ..:..
  Fly   203 KQVACFHCGELFRTKTTLF----DHLRRQPENNTNSFQCAQCFKFFATKKLLKSHVV---RHVNC 260

  Fly   422 YVCDLCGKSFNYITGLKDH-KLVHTDECPFECPVCKRGFKNNARLKIHLD-THSAEIYEC--TVC 482
            |.|.:|..:.:..:.|..| :..|..:.|.:|..|.......:.|..|:. .||..:::|  ..|
  Fly   261 YKCTMCDMTCSSASSLTTHIRYRHLKDKPLKCSECDTRCVRESDLAKHVQIVHSKTVHQCEHPDC 325

  Fly   483 GLKLKTRRTFNKHKL-VHSDTR-QFKCEVCGSAFKRSKTLKAHLILHTGIRPYKCNFCGRDFANG 545
            ...::|.....:|.| ||.:.. .:.|..|...||..|:|.|||:...|.|          ..:|
  Fly   326 HYSVRTYTQMRRHFLEVHGNNPILYACHCCERFFKSGKSLSAHLMKKHGFR----------LPSG 380

  Fly   546 SNCRSHKRQA--------HPKELAEEEARGVTRSTLLPMLDELTIASKLLKTPAGPC 594
                 |||..        :..|....|:..||:..|.|.:::     .|.|...|.|
  Fly   381 -----HKRFTYRVDENGFYRLETTRLESLEVTQQILSPQVND-----SLAKPGTGSC 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6254	NP_649983.2	zf-AD	21..99	CDD:285071
		COG5048	<353..554	CDD:227381	51/209 (24%)
		C2H2 Zn finger	364..384	CDD:275368	5/19 (26%)
		C2H2 Zn finger	395..416	CDD:275368	8/20 (40%)
		C2H2 Zn finger	424..444	CDD:275368	4/20 (20%)
		C2H2 Zn finger	452..472	CDD:275368	4/20 (20%)
		C2H2 Zn finger	479..499	CDD:275368	5/22 (23%)
		C2H2 Zn finger	507..527	CDD:275368	9/19 (47%)
		zf-H2C2_2	520..544	CDD:290200	6/23 (26%)
		C2H2 Zn finger	535..553	CDD:275368	2/17 (12%)
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	3/16 (19%)
		C2H2 Zn finger	207..225	CDD:275368	6/21 (29%)
		C2H2 Zn finger	237..257	CDD:275368	8/22 (36%)
		C2H2 Zn finger	263..284	CDD:275368	4/20 (20%)
		C2H2 Zn finger	292..311	CDD:275368	4/18 (22%)
		C2H2 Zn finger	352..373	CDD:275368	9/20 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444636
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930