Protein Alignment CG6254 and CG4707

DIOPT Version :10

• Sequence 1: NP_649983.2
• Gene: CG6254 / 41244
• FlyBaseID: FBgn0037794
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_611944.1
• Gene: CG4707 / 37935
• FlyBaseID: FBgn0035036
• Length: 673
• Species: Drosophila melanogaster
• Alignment Length: 671
• Identity: 146/671 - (21%)
• Similarity: 242/671 - (36%)
• Gaps: 172/671 - (25%)

  Fly    71 LCSECFTLMDCLIEFSERVRKVQILFSKLQLLQSNNLMDYEKIREDCGVATDG----WKHIMLGA 131
            :|.||:..:....||.:||       |.|...:|::... |.| |.||...:.    ...:.|.|
  Fly    49 VCRECWNCVSSFEEFHQRV-------SCLHRQRSSDSKS-EPI-EFCGQTEEAIINPLYSVELDA 104

  Fly   132 VDESL--PQNDEVFISEEQPIVCQTETSSKMKSEI------LMIPNFLVEKQCLQEKQDFPKEED 188
            :.|:.  |...:|.::|.:|:.........:|:||      |.:||           :..|..:.
  Fly   105 LAEAFFAPSEVKVEVNELEPLPKVELLEDPVKTEIRTAPKRLGVPN-----------EGSPHSKR 158

  Fly   189 VIEEEMQISGVEEEILEEDVEEDLAEEEVETVEEEIDTVG-----------------EEVEAVEE 236
            .|:.|:.:....:..|.:.:..|.....|...:......|                 |...:.::
  Fly   159 RIKNELPVDSDSDAPLADFLNSDSKRSSVGPAKNSEANKGRQLRRSARRGRPPKAKPESAPSPKK 223

  Fly   237 ELETQDA---------TDCLVEEVEHMTEDRYIEESQIIEESQVSDFNM------ETY-EI---V 282
            ||:::|.         .:.:..|....|:|.....|:  ...:.||.::      |.| ||   |
  Fly   224 ELDSEDGEENARDNNDMEFVAPEAVLGTDDSSSSSSE--SSGEDSDHSLPDIEPEERYAEIPKRV 286

  Fly   283 QHNPQKEPVETKDTVESIESNEDTQEDISREHV-TDEEDEISEVPAMYK---CNICKKPYKKPKA 343
            ...|:|.....|..|..:..   ::|:|.|..: .||.|||  :...:|   |::|....:....
  Fly   287 VVKPKKYRKREKPLVPPVRL---SREEIERRKLQQDEYDEI--ILQFFKKFPCSLCNLLVQNFAD 346

  Fly   344 YKRHMEEVHN-----------------------TVADDLPQLECNQCKLCFPTVAQLHAHHRTH- 384
            .:||....||                       .|..:.....|:||...|.....|..|.:||
  Fly   347 MRRHQRVSHNIESGYIECCGRKFHLRKALAEHVLVHKNPDHFMCSQCGRVFQDSRALEVHEQTHT 411

  Fly   385 ---VRAKPK------TDNC---------------------------CPHCEKRFTTSGTLKRHIE 413
               |:|:||      .:.|                           ||.|.|:..|...||.|:.
  Fly   412 NPEVKAEPKEKRIYQCEKCPKSFTTKAAMEYHDVSKHVPKSEFKYSCPECNKKIPTERKLKEHLR 476

  Fly   414 GIHNQIKPYVCDLCGKSFNYITGL-KDHKLVHTDE-----CPFECPVCKRGFKNNARLKIHLDT- 471
            .:|:.....:||.|||:....|.| |.|:|.|:::     .|.:|.:|....::.:.||.|:.|
  Fly   477 YMHDPEAAIICDKCGKTLRSQTNLKKHHELEHSEKPRPKPDPVQCEICGTWLRHLSGLKQHMKTV 541

  Fly   472 HS--AEIYECTVCGLKLKTRRTFNKHKLVHSD--TRQFKCEVCGSAFKRSKTLKAHLILHTGIRP 532
            |.  .:.:.|.:|.......|...:| :.|:.  .|:|||.:|..||||.:.|:.|...|||...
  Fly   542 HEPPGDEHRCHICNKTSTNSRALKRH-IYHNHLCERKFKCGMCEKAFKRPQDLREHTSTHTGEVL 605

  Fly   533 YKCNFCGRDFANGSNCRSHKRQAHPKELAEEEARGVTRSTLLPMLDELTIASKLLKTPAGPCKVK 597
            |.|..|...|.:.:|...|:::.|..|...:..:        |:             |....|:.
  Fly   606 YTCPNCPMTFFSNANMYKHRQRLHRAEWEADRKK--------PL-------------PPNIMKIS 649

  Fly   598 GSRPKAAPKDQDNGNESPTKD 618
            .....|..|.|.:|...|..:
  Fly   650 QGATTAMKKRQTSGALFPQSE 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6254	NP_649983.2	zf-AD	21..99	CDD:462262	8/27 (30%)
		COG5048	<353..554	CDD:227381	68/271 (25%)
		C2H2 Zn finger	364..384	CDD:275368	6/19 (32%)
		C2H2 Zn finger	395..416	CDD:275368	8/20 (40%)
		C2H2 Zn finger	424..444	CDD:275368	10/20 (50%)
		C2H2 Zn finger	452..472	CDD:275368	6/20 (30%)
		C2H2 Zn finger	479..499	CDD:275368	4/19 (21%)
		C2H2 Zn finger	507..527	CDD:275368	8/19 (42%)
		C2H2 Zn finger	535..553	CDD:275368	5/17 (29%)
CG4707	NP_611944.1	zf-AD	3..77	CDD:462262	10/34 (29%)
		C2H2 Zn finger	334..355	CDD:275368	4/20 (20%)
		LIM	<361..407	CDD:413332	6/45 (13%)
		C2H2 Zn finger	365..382	CDD:275368	0/16 (0%)
		C2H2 Zn finger	390..410	CDD:275368	6/19 (32%)
		C2H2 Zn finger	427..443	CDD:275368	1/15 (7%)
		COG5236	<455..>574	CDD:227561	33/119 (28%)
		C2H2 Zn finger	458..476	CDD:275368	8/17 (47%)
		C2H2 Zn finger	487..507	CDD:275368	9/19 (47%)
		C2H2 Zn finger	521..540	CDD:275368	5/18 (28%)
		C2H2 Zn finger	551..572	CDD:275368	5/21 (24%)
		C2H2 Zn finger	580..600	CDD:275368	8/19 (42%)
		C2H2 Zn finger	608..629	CDD:275368	5/20 (25%)