DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6254 and Zfp462

DIOPT Version :9

Sequence 1:NP_649983.2 Gene:CG6254 / 41244 FlyBaseID:FBgn0037794 Length:634 Species:Drosophila melanogaster
Sequence 2:XP_038966959.1 Gene:Zfp462 / 362522 RGDID:1562123 Length:2565 Species:Rattus norvegicus


Alignment Length:571 Identity:114/571 - (19%)
Similarity:189/571 - (33%) Gaps:173/571 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   135 SLPQNDEVFISEEQPIVCQTETSSKMKSEILMIPNF----LVEKQCLQEKQDFPKEEDVIEEEMQ 195
            |.|::|...:|||     ......|.|..:....:|    :|.....:....|||::...:....
  Rat  1745 SPPKDDSPQLSEE-----LRRAVEKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGY 1804

  Fly   196 ISGV---EEE---ILEEDVEEDLAEEEVETVEEEIDTVGEE-VEAVEEELETQDATDCLVEEVEH 253
            .:.|   |.|   ::||:........|||...::|:.:... ::..:....|.:.. |:     |
  Rat  1805 FTAVYADEHEKPPLMEEEGRSGFERPEVEGEAQDIEWLPFRCIKCFKLSFSTAELL-CM-----H 1863

  Fly   254 MTE--DRYIEESQIIEES----QVSDFN--------METYEIVQH-NPQKEPVETKDTVESIESN 303
            .|:  .|.::...:|..|    |.|.|.        ..|.|:..| |...|..:.:     .:..
  Rat  1864 YTDHHSRDLKRDFVILGSGPRFQNSTFQCKHCDSKLQSTAELTSHLNIHNEEFQKR-----AKRQ 1923

  Fly   304 EDTQEDISREHVTD-------EE---DEISEVPAM-------YKCNICKKPYKKPKAYKRHMEEV 351
            |..::.:|::...|       :|   ..:.|.|.:       |||..|              .||
  Rat  1924 ERRKQLLSKQKYADGAFADFKQERPFGHLEEAPKIKERKVVGYKCKFC--------------VEV 1974

  Fly   352 HNTVADDLPQLECNQCKLCFPTVAQLHAHHRTHVR--------AKPKTDNCCP-HC-----EKRF 402
            |                   ||:..:..|.|.||:        |..|.:...| |.     |...
  Rat  1975 H-------------------PTLRAICNHLRKHVQYGSVPAVSAAVKQEAEDPSHLFLDGFEAAR 2020

  Fly   403 TTSGTLKRHIEGIH--------NQIKP--YVCDLCGKSFNYITGLKDHKLVH------TDECPFE 451
            ..||||...::|.|        ::.:|  |.|..|.:....:.||:.|:..|      |.|..:.
  Rat  2021 DASGTLVGRVDGGHCLLDGMLEDETRPGGYHCSQCDRVLMSMQGLRSHERSHLALAMFTREDKYS 2085

  Fly   452 CPVCK--RGFKNNARLKIHLDTHSAEIYECTVCGLKLKTRRTFNKHKLVHSDTRQFKCEVCGSAF 514
            |..|.  ..|::|  |..|:.||                          |...:.|:|::|....
  Rat  2086 CQYCSFVSAFRHN--LDRHMQTH--------------------------HGHHKPFRCKLCSFKS 2122

  Fly   515 KRSKTLKAHLI-LHTGIRPYKCNFCGRDFANGSNCRSHKRQAHPKELAEEEARGVTRSTLLPMLD 578
            ..:..||.|:: .|.|...|||::|.......|..:.|..:.|.|.|.      :.|..::.:|.
  Rat  2123 SYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVHGKALT------LPRPRIVSLLS 2181

  Fly   579 ELTIASKLLKTPAGPCKVKGSRPKAAPKD--------------QDNGNESP 615
            .....|....|||...:.......:.|.|              ::|...||
  Rat  2182 SHAHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNSRVSP 2232

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6254NP_649983.2 zf-AD 21..99 CDD:285071
COG5048 <353..554 CDD:227381 50/233 (21%)
C2H2 Zn finger 364..384 CDD:275368 4/19 (21%)
C2H2 Zn finger 395..416 CDD:275368 8/26 (31%)
C2H2 Zn finger 424..444 CDD:275368 5/19 (26%)
C2H2 Zn finger 452..472 CDD:275368 6/21 (29%)
C2H2 Zn finger 479..499 CDD:275368 0/19 (0%)
C2H2 Zn finger 507..527 CDD:275368 5/20 (25%)
zf-H2C2_2 520..544 CDD:290200 9/24 (38%)
C2H2 Zn finger 535..553 CDD:275368 4/17 (24%)
Zfp462XP_038966959.1 C2H2 Zn finger 2052..2072 CDD:275368 5/19 (26%)
zf-H2C2_5 2084..2108 CDD:404746 8/51 (16%)
C2H2 Zn finger 2086..2106 CDD:275368 6/21 (29%)
C2H2 Zn finger 2115..2136 CDD:275368 5/20 (25%)
C2H2 Zn finger 2144..2165 CDD:275368 4/20 (20%)
C2H2 Zn finger 2315..2335 CDD:275368
C2H2 Zn finger 2361..2381 CDD:275368
C2H2 Zn finger 2389..2410 CDD:275368
C2H2 Zn finger 2475..2495 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24403
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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