Protein Alignment CG6254 and LOC1279969

DIOPT Version :10

• Sequence 1: NP_649983.2
• Gene: CG6254 / 41244
• FlyBaseID: FBgn0037794
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: XP_061514535.1
• Gene: LOC1279969 / 1279969
• VectorBaseID: AGAMI1_012132
• Length: 545
• Species: Anopheles gambiae
• Alignment Length: 634
• Identity: 195/634 - (30%)
• Similarity: 288/634 - (45%)
• Gaps: 109/634 - (17%)

  Fly    16 TIWHQWCRLCSKEHPTNQNVFFREAKQNSWASTMAMTIGKYFWVDIKREDELSNFLCSECFTLMD 80
            |.|..|||||::|....:....|:..         ..||.:|.|.:......:..:|.||...::
Mosquito     3 TSWKSWCRLCAEEKALLKLESVRDVN---------AVIGNFFNVSLIEIKGTAANICEECLGFVN 58

  Fly    81 CLIEFSERVRKVQILFSKL--QLLQSNNLMDYEKIREDCGVATDGWKHIMLGAVDESLPQNDEVF 143
            .|..|..|..:...||:.|  .|....:.:|.::||.         |::     ||.||.:.:..
Mosquito    59 KLEHFEARCHQTNQLFTYLAKHLPDETHPLDLKQIRS---------KYL-----DEMLPNDGDEE 109

  Fly   144 ISEEQPIVCQTETSSKMKSEILMIPNFLVEKQCLQEKQDFPKEEDVIEEEMQISGVEEEILEEDV 208
            :.|      ..|..|:...|:|.|...|       |.||..:...|.::..::....|.:....|
Mosquito   110 LFE------VLEAESERAKELLSIDPVL-------ETQDIQELGKVADDNTEVLYQVESLTVSSV 161

  Fly   209 EEDLAEEEVETVEEEIDTVGEEVEAVEEELETQDATDCLVEEVEHMTEDRYIEESQIIEESQVSD 273
            :.:|.....||  |:.:.:..:::.....|||.|                     :.:||.:...
Mosquito   162 QNELENNANET--EQWEMLEVDMDDCSNGLETND---------------------ENVEEEEFDK 203

  Fly   274 FNMETYEIVQHNPQKEPVETKDTVESIESNEDTQEDISREHVTDEEDEISEVPAMYKCNICKKPY 338
            |:...||          .||..:....:..:...:|.| |...|.:||  .|||
Mosquito   204 FSDSDYE----------PETSGSASGTKREQSKGKDDS-ESPIDGDDE--SVPA----------- 244

  Fly   339 KKPKAYKRHMEEVHNTVADDLPQLECNQCKLC---FPTVAQLHAHHRTHVRAKPKTDNCCPHCEK 400
                  |:..:..:.|.....|..:.:|||.|   |...:||..|...|:....|....|..|.|
Mosquito   245 ------KQLQKRRYTTTRGASPNQQVHQCKYCRKTFKCNSQLTRHEYIHLTQDGKPRYSCEICRK 303

  Fly   401 RFTTSGTLKRHIEGIHNQIKPYVCDLCGKSFNYITGLKDHKLVHTDECPFECPVCKRGFKNNARL 465
            .||.|...:.|:..:|...|||:|:.|||.|:....||:|.:||::|.||:|..|.:.|||..||
Mosquito   304 VFTKSSIRRAHMRMMHEGAKPYMCEECGKPFSSKGALKEHYIVHSEERPFKCAYCPKSFKNAPRL 368

  Fly   466 KIHLDTHSAEIYECTVCGLKLKTRRTFNKHKLVHSDTRQFKCEVCGSAFKRSKTLKAHLILHTGI 530
            |.|.|||:..:|.|..|||||.|:||.|.|.:||||.::|||:.||:.:||||.||||||||||:
Mosquito   369 KTHEDTHNDTLYVCPHCGLKLNTKRTLNMHMVVHSDQKKFKCQECGNEYKRSKALKAHLILHTGL 433

  Fly   531 RPYKCNFCGRDFANGSNCRSHKRQAHPKELAEEEARGVTR-STLLPMLDELTIASKLLKTPAGPC 594
            |||:|.||.:.|||||||||||::.||:|||..||.|..: :..:|.|:.|...|   ::.....
Mosquito   434 RPYQCPFCDKTFANGSNCRSHKKKFHPRELAALEAAGGQKPAANIPKLEHLQRKS---QSDGEGV 495

  Fly   595 KV--KGSRPKAAPKDQDNGNE--------SPTKDTDGA-ILYELVEELD 632
            ::  |..|..|...:.:.|.|        :...||||: |..||..||:
Mosquito   496 EITRKHIRSTARASNSNRGKERQEQLTLTADEADTDGSPIKSELKMELN 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6254	NP_649983.2	zf-AD	21..99	CDD:462262	19/77 (25%)
		COG5048	<353..554	CDD:227381	100/203 (49%)
		C2H2 Zn finger	364..384	CDD:275368	8/22 (36%)
		C2H2 Zn finger	395..416	CDD:275368	7/20 (35%)
		C2H2 Zn finger	424..444	CDD:275368	8/19 (42%)
		C2H2 Zn finger	452..472	CDD:275368	10/19 (53%)
		C2H2 Zn finger	479..499	CDD:275368	11/19 (58%)
		C2H2 Zn finger	507..527	CDD:275368	13/19 (68%)
		C2H2 Zn finger	535..553	CDD:275368	13/17 (76%)
LOC1279969	XP_061514535.1	None