Protein Alignment CG6254 and znf335

DIOPT Version :10

• Sequence 1: NP_649983.2
• Gene: CG6254 / 41244
• FlyBaseID: FBgn0037794
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: XP_004918689.2
• Gene: znf335 / 100498615
• XenbaseID: XB-GENE-981913
• Length: 1427
• Species: Xenopus tropicalis
• Alignment Length: 636
• Identity: 138/636 - (21%)
• Similarity: 217/636 - (34%)
• Gaps: 167/636 - (26%)

  Fly   130 GAVDE--SLPQNDEVFISEEQPIVCQTETSSKMKSEILMIPNFLVEKQCLQEKQDFPKEEDV--- 189
            |:||.  :.|.|.::.   :..||...|.|:   ||   |..:|:    ||| ||......|
 Frog   398 GSVDGIINAPINPQII---QGCIVANPEGSN---SE---ITQYLI----LQE-QDSTSSVTVASV 448

  Fly   190 -IEEEMQISG--------VEEEILEEDVE-----------------------EDLAEEEVE--TV 220
             :.|..|..|        .:.|.||..||                       ..:.|..::  ::
 Frog   449 PVGERYQTHGSSCAAESMADAESLEGMVEVVFVQQYKCKMCKYKSTSKPTLLRHVRERHIQPTSI 513

  Fly   221 EEEIDTVGEEVEAVEEELETQDATDCLVEEVEHMTEDRYIEESQIIEESQVSDF---------NM 276
            ||:....|:...:.|||.|.:|             :|..::...|.:.:..||:         |:
 Frog   514 EEKRSHEGKVARSKEEEEEEED-------------DDDIVDAGAIDDPNDDSDYSPGEDTPNNNL 565

  Fly   277 ETYE--IVQHNPQKEP---------------------------------VETKDTVESIESNEDT 306
            |:..  :::..|:::|                                 :|.||......|.|.:
 Frog   566 ESAHGILIKERPRRKPGRPRKIPRIDGPKLDIPLSSNDNQTDQGVTNSDLENKDPASLAISEEQS 630

  Fly   307 QEDISR----EHVTDEEDEISEVPAMYK-----------CNICKKPYKKPKAYKRHMEEVHNTVA 356
            .....|    :|:..::.........|:           |.||...:.....:..|   |.:.|.
 Frog   631 PPKRMRGRPPKHIRGKKYRRFRGSRFYRPPSKRLLRPFICRICGSSFLTHDDFTFH---VTSHVG 692

  Fly   357 DDLPQLECNQCKLCFPTVAQLHAHHRTHVRAKPKTDNCCPHCEKRFTTSGTLKRHIEGIHNQ--- 418
            :|....:|.||.......:.|..|...|..:||..   |..||........:.|| ..:|.:
 Frog   693 NDPQAFQCQQCSYQCRRWSSLKEHMYNHKGSKPYK---CEECEYTSVYKKDVVRH-SAVHREDRK 753

  Fly   419 ------IKP--YVCDLCGKSFNYITGLKDHKLVHTDECPFECPVCKRGFKNNARLKIHLDTH--- 472
                  .||  |.|.:||:.:.....|..|..:|:.|.|..|..|.:.||.....|:||.||
 Frog   754 KKSEKTSKPASYPCPVCGRIYTMQKRLTQHMKIHSAEKPHMCDKCGKAFKKRYTFKMHLLTHLQC 818

  Fly   473 -SAEIYECTVCGLKLKTRRTFNKHKLVHSDTRQFKCEVCGSAFKRSKTLKAHLIL-HTGIRPYKC 535
             ....|:|..|......|:....|:|.|.:.:.|||..|.....|...|.:|:.. |.|.:|:.|
 Frog   819 VGKSRYKCEFCEYICGDRKQLLNHQLTHMNDKPFKCSQCKYHTYRQDFLLSHMATKHAGGKPFAC 883

  Fly   536 NFCGRDFANGSNCRSHKRQAHPKELAEEEAR--GVTRSTLLPMLDELTIASKLLKTPAGPCKVKG 598
            :.|.....:..|.|.|.:..||....|...|  ..|.|...|......|..  ||......:.:|
 Frog   884 DHCHFTTKHKKNLRLHVQSRHPLLYNEWSQRHPEETPSRRRPFFSMQQIEE--LKQLHEQSENQG 946

  Fly   599 SRPKAAPKDQ--------DNGNESPTKDTD------GAILYELV-EELDYS 634
            ..|:....|.        ...::|||::..      .||:||.. ||.:|:
 Frog   947 PSPQEVVMDAAELSYQILQPTSQSPTEEQSHGALGAAAIIYEQEGEEEEYA 997

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6254	NP_649983.2	zf-AD	21..99	CDD:462262
		COG5048	<353..554	CDD:227381	58/216 (27%)
		C2H2 Zn finger	364..384	CDD:275368	5/19 (26%)
		C2H2 Zn finger	395..416	CDD:275368	5/20 (25%)
		C2H2 Zn finger	424..444	CDD:275368	5/19 (26%)
		C2H2 Zn finger	452..472	CDD:275368	7/19 (37%)
		C2H2 Zn finger	479..499	CDD:275368	5/19 (26%)
		C2H2 Zn finger	507..527	CDD:275368	5/20 (25%)
		C2H2 Zn finger	535..553	CDD:275368	5/17 (29%)
znf335	XP_004918689.2	C2H2 Zn finger	670..690	CDD:275368	5/22 (23%)
		C2H2 Zn finger	700..720	CDD:275368	5/19 (26%)
		zf-H2C2_2	712..737	CDD:463886	8/27 (30%)
		C2H2 Zn finger	728..748	CDD:275368	5/20 (25%)
		C2H2 Zn finger	767..787	CDD:275368	5/19 (26%)
		zf-H2C2_2	779..804	CDD:463886	8/24 (33%)
		C2H2 Zn finger	795..815	CDD:275368	7/19 (37%)
		C2H2 Zn finger	826..846	CDD:275368	5/19 (26%)
		C2H2 Zn finger	854..875	CDD:275368	5/20 (25%)
		C2H2 Zn finger	883..904	CDD:275368	5/20 (25%)
		C2H2 Zn finger	1178..1198	CDD:275368
		C2H2 Zn finger	1206..1226	CDD:275368
		C2H2 Zn finger	1234..1255	CDD:275368