DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TAF1B and RRN7

DIOPT Version :9

Sequence 1:	NP_001262451.1	Gene:	TAF1B / 41242	FlyBaseID:	FBgn0037792	Length:	872	Species:	Drosophila melanogaster
Sequence 2:	NP_012509.1	Gene:	RRN7 / 853428	SGDID:	S000003562	Length:	514	Species:	Saccharomyces cerevisiae

Alignment Length:	536	Identity:	98/536 - (18%)
Similarity:	180/536 - (33%)	Gaps:	172/536 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   274 NMVEDDIQLSDLLRFIDEEHL--------TKRCMLNYLPGNVAAKGKALLKDMELSKMKDKVTNK 330
            :::|.|::.:|     ||:.|        |:|  ||.......:...:.|.:.:|.:.:.:.::|
Yeast    33 HVMEGDVEFND-----DEDDLNGLGAGVITRR--LNLTTNATGSFQSSQLTNSQLLQQQQRQSHK 90

  Fly   331 LLRVNIACMSRFINLSEYQ---KPNLHSLAERYILELALPPRLLKYVNSLLDLHPPTFFNAMTVH 392
            ..:..|...::.:.|..:|   |..:..|    |.|:.. |:..::|..::.|.     ...|::
Yeast    91 KFKKLIGHEAKLLFLKSFQFILKRQIRWL----ITEMRF-PKEFEHVAKIIWLK-----ILKTIN 145

  Fly   393 PYPRYEARTMAYILYAMKLLFGLDDLKERNISESAAKINEKLLEVGGDEAPLLFVFT----EWME 453
            ..|:.|.:...::...:.:|:    |...::|                    |.|:|    :|:.
Yeast   146 DQPQEELKLQLHMTSTISILY----LASTHLS--------------------LPVYTCDYIKWIC 186

  Fly   454 FVEMRKVIVSHYNQSFARRFGVSTRTGCQVDDILAKEWKEKEQGETFGWMQGS-AAMKRQHENLT 517
            ..:|...                     |..:||.|.|:.:........::|| :....|..|..
Yeast   187 TAKMPYF---------------------QASEILPKSWRIQLPNYYVSILEGSISPFNGQLYNKI 230

  Fly   518 HIIETMLKDHFGESSKESMEKE--------HIEFQPSLTPAHSYFNRILLQVSRSDGAKMKITIP 574
            .:...|:  ||    ||....|        .:..|.:|.|...::.:.:::...:|  ...:|:.
Yeast   231 ALTCGMI--HF----KEFFNSEISCQGLLLKLVMQCALPPEFYFYTKQVIEFEETD--IRNLTLW 287

  Fly   575 DHMKVDHSARNLDPFVLETTELSQYLSQHGLKLRVEELACQEDIQNVGIFRPLTIIRGDGREYRA 639
            :.....|:.|               :|.|. :|||           :..|. |||
Yeast   288 ERTDERHTGR---------------VSNHA-ELRV-----------LSYFM-LTI---------- 314

  Fly   640 NTEIKTETWISELKRKEKRP-------DFRFTQPTGT---YGARYLKRI-----TMRDARRVQLE 689
                   .|:....|..:.|       ....||.|.|   .|...:|.:     |..|..:
Yeast   315 -------NWMLSFDRDRQYPLKWILSLTESLTQRTTTSESIGRNIVKVVYPDKPTSSDYFQ---- 368

  Fly   690 INNPFWDVTETPSFLLKLNDNEIPLDSLSSLQTFEEGTMDPLNIPLDLPRRNLEKIL------NP 748
                 |...||..||..:....:|..: .||.. |.|:|: :.|...:.||.|.||.      |.
Yeast   369 -----WSEEETLEFLKWMEKQFLPTQT-KSLHN-ENGSME-MTIDQKIARRKLYKIFPLDREANH 425

  Fly   749 EGSDRASDQVASDIND 764
            :|....|....:.|.|
Yeast   426 DGEFNDSTHQLTFIED 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TAF1B	NP_001262451.1	RRN7	8..40	CDD:288614
RRN7	NP_012509.1	zf-RRN7	4..37	CDD:403092	0/3 (0%)
RRN7	NP_012509.1	SAM_superfamily	363..>399	CDD:417767	10/46 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR31576
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100