DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaSnap2 and napgb

DIOPT Version :9

Sequence 1:	NP_649980.1	Gene:	gammaSnap2 / 41239	FlyBaseID:	FBgn0266721	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_001002469.1	Gene:	napgb / 436742	ZFINID:	ZDB-GENE-040718-171	Length:	311	Species:	Danio rerio

Alignment Length:	286	Identity:	91/286 - (31%)
Similarity:	154/286 - (53%)	Gaps:	32/286 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 AKKIEEAEALIGQT---------------DSAANEYAKAGMYFKAATAYRIAKSFDKRKDCLLKA 55
            |:||.||...|.:.               |.||:|.|      |||.|::.||.|::.||..||.
Zfish     3 AQKINEAHDHITKAEKCLKTSMTKWKPDYDGAASEMA------KAAVAFKNAKQFEQAKDAYLKE 61

  Fly    56 IDCYENNKSWFHAAKSYEQIILLAKETDKLSEVEDYANRACCLYQQHGSPEAAAAALDKAAKMTE 120
            .:.:..||:.|||||:|||..::.|:..|:.|......:|..:|.::|:...|..|||:|.|:.|
Zfish    62 AEYHTENKALFHAAKAYEQAGMMLKDMKKMPEAIQLIEKASIMYVENGTSGTAGMALDRAGKLIE 126

  Fly   121 SKHPDLALGFYKRALAVVLIGDSTHQASEFASKVSRILVRLKKYEEATKALKKEISLNLQTKSYG 185
            ....:.|:..|::|.:|....|...||:|...|.||:||||::.:||..||:||.::..:.::|.
Zfish   127 PIDLEKAVDLYQKAASVFENEDRLRQAAELLGKSSRLLVRLRRLDEAAVALQKEKNMYKEIENYP 191

  Fly   186 QVGRLVVALILVQLTLEDYVDAKKTFKK-------WGNRCDPQEVNTLQNLLKAFDDEDPELATK 243
            ...:..:|.:||.|...|:|.|.|..::       .|:    ::..:::.||.|||::|.:..::
Zfish   192 TCFKKTIAQVLVHLHRGDFVAADKCVRESYSLPGFSGS----EDCVSMETLLAAFDEQDEDGVSR 252

  Fly   244 MLASPFIRHMDVEYALLSKDVPLPKG 269
            :..||.:::||.:||.|:..:.:|.|
Zfish   253 VCNSPLLKYMDNDYAKLAISLKVPGG 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaSnap2	NP_649980.1	SNAP	29..239	CDD:305195	71/216 (33%)
		TPR repeat	29..61	CDD:276937	11/31 (35%)
		TPR repeat	65..102	CDD:276937	13/36 (36%)
		TPR repeat	105..140	CDD:276937	11/34 (32%)
		TPR repeat	144..180	CDD:276937	16/35 (46%)
napgb	NP_001002469.1	SNAP	8..276	CDD:305195	86/277 (31%)
		SNAP	8..254	CDD:291599	79/255 (31%)
		TPR repeat	30..67	CDD:276937	16/42 (38%)
		SLR repeat	50..80	CDD:276807	13/29 (45%)
		TPR repeat	71..108	CDD:276937	13/36 (36%)
		SLR repeat	87..119	CDD:276807	7/31 (23%)
		TPR repeat	111..146	CDD:276937	11/34 (32%)
		TPR repeat	150..186	CDD:276937	16/35 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595434
Domainoid	1	1.000	193	1.000	Domainoid score	I3143
eggNOG	1	0.900	-	-		E1_KOG1585
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2838
Inparanoid	1	1.050	224	1.000	Inparanoid score	I3493
OMA	1	1.010	-	-		QHG55184
OrthoDB	1	1.010	-	-		D1540214at2759
OrthoFinder	1	1.000	-	-		FOG0003744
OrthoInspector	1	1.000	-	-		mtm6409
orthoMCL	1	0.900	-	-		OOG6_103437
Panther	1	1.100	-	-	O	PTHR13768
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4180
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.770