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Protein Alignment CAH7 and CA9

DIOPT Version :9

Sequence 1:	NP_001287267.1	Gene:	CAH7 / 41238	FlyBaseID:	FBgn0037788	Length:	304	Species:	Drosophila melanogaster
Sequence 2:	NP_001207.2	Gene:	CA9 / 768	HGNCID:	1383	Length:	459	Species:	Homo sapiens

Alignment Length:	284	Identity:	80/284 - (28%)
Similarity:	130/284 - (45%)	Gaps:	41/284 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 NEWGYPDLDNNQDEPFPKWGGLCDSGKKQSPINLHVK-----GALKGEFDALKFENYDEHQKNLR 79
            :.|.|     ..|.|:|:....| :|:.|||:::..:     .||: ..:.|.|:.  .....||
Human   139 SHWRY-----GGDPPWPRVSPAC-AGRFQSPVDIRPQLAAFCPALR-PLELLGFQL--PPLPELR 194

  Fly    80 MVNNGHSIQLS---GFDHELTLSGGALLQDFVVEQIHMHW------WSEHTINDIRYPLEVHIVH 135
            :.|||||:||:   |.  |:.|..|   :::...|:|:||      .||||:...|:|.|:|:||
Human   195 LRNNGHSVQLTLPPGL--EMALGPG---REYRALQLHLHWGAAGRPGSEHTVEGHRFPAEIHVVH 254

  Fly   136 RNTIYPNMTMAANFKDGIVVIGVLYHVSNTPNEAIGSIIKSLGAVKSYDSMNKPVLVADSLAVDD 200
            .:|.:..:..|.....|:.|:..........|.|...::..|..:....|..:    ...|.:..
Human   255 LSTAFARVDEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIAEEGSETQ----VPGLDISA 315

  Fly   201 LVPS-VENYFTYAGSLTTPTCAEAVTWIVLTETFPVTLDQVNEFKEIEYDEG-KQLHNNYRELQS 263
            |:|| ...||.|.||||||.||:.|.|.|..:|..::..|::...:..:..| .:|..|:|..|.
Human   316 LLPSDFSRYFQYEGSLTTPPCAQGVIWTVFNQTVMLSAKQLHTLSDTLWGPGDSRLQLNFRATQP 380

  Fly   264 ENNRAVVLVEQPEQRSGSAGLTAS 287
            .|.|.:       :.|..||:.:|
Human   381 LNGRVI-------EASFPAGVDSS 397

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.