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Protein Alignment CAH7 and CA3

DIOPT Version :9

Sequence 1:	NP_001287267.1	Gene:	CAH7 / 41238	FlyBaseID:	FBgn0037788	Length:	304	Species:	Drosophila melanogaster
Sequence 2:	NP_005172.1	Gene:	CA3 / 761	HGNCID:	1374	Length:	260	Species:	Homo sapiens

Alignment Length:	282	Identity:	81/282 - (28%)
Similarity:	124/282 - (43%)	Gaps:	59/282 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 ANEWGY-----PDLDNNQDEPFPKWGGLCDSGKKQSPINLHVKGALKGEFDALKFENYDEHQKNL 78
            |.||||     ||   :..|.||.     ..|:.|||:.||.|..              .|..:|
Human     2 AKEWGYASHNGPD---HWHELFPN-----AKGENQSPVELHTKDI--------------RHDPSL 44

  Fly    79 R-------------MVNNGHSIQL---SGFDHELTLSGGALLQDFVVEQIHMHW------WSEHT 121
            :             ::|||.:.::   ..:|..: |.||.|...:.:.|.|:||      .||||
Human    45 QPWSVSYDGGSAKTILNNGKTCRVVFDDTYDRSM-LRGGPLPGPYRLRQFHLHWGSSDDHGSEHT 108

  Fly   122 INDIRYPLEVHIVHRNTIYPNMTMAANFKDGIVVIGVLYHVSNTPNEAIGSIIKSLGAVKSYDSM 186
            ::.::|..|:|:||.|..|.....|...:|||.|||:...:.: .|......:.:|..:|: ...
Human   109 VDGVKYAAELHLVHWNPKYNTFKEALKQRDGIAVIGIFLKIGH-ENGEFQIFLDALDKIKT-KGK 171

  Fly   187 NKPVLVADSLAVDDLVPSVENYFTYAGSLTTPTCAEAVTWIVLTETFPVTLDQVNEFKEI----E 247
            ..|....|...   |.|:..:|:||.||.|||.|.|.:.|::|.|...|:.||:.:.:.:    |
Human   172 EAPFTKFDPSC---LFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAE 233

  Fly   248 YDEGKQLHNNYRELQSENNRAV 269
            .:....|.:|:|..|..|||.|
Human   234 NEPPVPLVSNWRPPQPINNRVV 255

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.