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Protein Alignment CAH7 and CA1

DIOPT Version :9

Sequence 1:	NP_001287267.1	Gene:	CAH7 / 41238	FlyBaseID:	FBgn0037788	Length:	304	Species:	Drosophila melanogaster
Sequence 2:	NP_001122301.1	Gene:	CA1 / 759	HGNCID:	1368	Length:	261	Species:	Homo sapiens

Alignment Length:	277	Identity:	76/277 - (27%)
Similarity:	126/277 - (45%)	Gaps:	52/277 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 EWGYPDLDNNQDEPFPKWGGL--CDSGKKQSPINLHVKGALKGEFDALKFENYDEHQKNLR---- 79
            :|||.|.:..:     :|..|  ..:|..|||:::..              :..:|..:|:
Human     5 DWGYDDKNGPE-----QWSKLYPIANGNNQSPVDIKT--------------SETKHDTSLKPISV 50

  Fly    80 ---------MVNNGHS--IQLSGFDHELTLSGGALLQDFVVEQIHMHW------WSEHTINDIRY 127
                     ::|.|||  :.....|:...|.||.....:.:.|.|.||      .||||::.::|
Human    51 SYNPATAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKY 115

  Fly   128 PLEVHIVHRNTI-YPNMTMAANFKDGIVVIGVLYHVSNTPNEAIGSIIKSLGAVKSYDSMNKPVL 191
            ..|:|:.|.|:. |.::..||:..||:.|||||..|... |..:..::.:|.|:|: .....|..
Human   116 SAELHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEA-NPKLQKVLDALQAIKT-KGKRAPFT 178

  Fly   192 VADSLAVDDLVPSVENYFTYAGSLTTPTCAEAVTWIVLTETFPVTLDQVNEFK----EIEYDEGK 252
            ..|.   ..|:||..:::||.||||.|...|:||||:..|:..|:.:|:.:|:    .:|.|...
Human   179 NFDP---STLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV 240

  Fly   253 QLHNNYRELQSENNRAV 269
            .:.:|.|..|....|.|
Human   241 PMQHNNRPTQPLKGRTV 257

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.