DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH7 and ca5b

DIOPT Version :9

Sequence 1:	NP_001287267.1	Gene:	CAH7 / 41238	FlyBaseID:	FBgn0037788	Length:	304	Species:	Drosophila melanogaster
Sequence 2:	NP_001039155.1	Gene:	ca5b / 733981	XenbaseID:	XB-GENE-1003819	Length:	319	Species:	Xenopus tropicalis

Alignment Length:	249	Identity:	79/249 - (31%)
Similarity:	129/249 - (51%)	Gaps:	21/249 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 PKWGGLCD--SGKKQSPINLHVKGALKGEFDALKFENYDEHQKNLRMVNNGHS--IQLSGFDHEL 96
            |.|.|..:  .|.:|||||:.::.::.....|.....||.: ..|.:.|||:|  ::......:.
Frog    52 PLWRGEIEVPGGSRQSPINIRIRDSVFHPQLAPVHTQYDPN-TCLYIWNNGYSFFVEYDDSTDKS 115

  Fly    97 TLSGGALLQDFVVEQIHMHW-----W-SEHTINDIRYPLEVHIVHRN-TIYPNMTMAANFKDGIV 154
            |:|||.|...|.::|.|.||     | ||||::...:|.|:|:||.| :.|.....|....:|:.
Frog   116 TVSGGPLENPFRLKQFHFHWGRNNDWGSEHTVDSRVFPAELHLVHWNCSKYRTFEEAIMEPNGLA 180

  Fly   155 VIGVLYHVSNTPNEAIGSIIKSLGAVKSYDSMNKPVLVADSLAVDDLVPSVENYFTYAGSLTTPT 219
            ||||...|.. .:|.:..::..|.:|:..|::.:......|.    |:||..:|:||:||||||.
Frog   181 VIGVFLKVGK-HHEKLQKLVDILPSVRYKDALTEFNYFDSSC----LLPSCGDYWTYSGSLTTPP 240

  Fly   220 CAEAVTWIVLTETFPVTLDQVNEFKEIEY----DEGKQLHNNYRELQSENNRAV 269
            ..|:||||::.:...|...|:..|:.:.:    :|.:.:.:|:|.||...||.|
Frog   241 LTESVTWIIMKKPIEVDHSQLAVFRSLLFTAVGEEERYMVDNFRPLQPLMNRTV 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH7	NP_001287267.1	alpha_CA	45..269	CDD:238200	75/236 (32%)
ca5b	NP_001039155.1	alpha_CA_V	63..298	CDD:239392	76/238 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010