DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH7 and ca16b

DIOPT Version :9

Sequence 1:	NP_001287267.1	Gene:	CAH7 / 41238	FlyBaseID:	FBgn0037788	Length:	304	Species:	Drosophila melanogaster
Sequence 2:	XP_001919055.3	Gene:	ca16b / 569183	ZFINID:	ZDB-GENE-080818-1	Length:	1382	Species:	Danio rerio

Alignment Length:	300	Identity:	74/300 - (24%)
Similarity:	130/300 - (43%)	Gaps:	60/300 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 WANEWGYPDLDNNQDEPFPKWGGLCDSGKKQSPIN-LHVKGALKGEFDALKFENYDEHQKN-LRM 80
            ||:  .||:               |.. :.|||:: |..:..:..|...|..:.::....| ..|
Zfish    66 WAS--AYPE---------------CGE-RNQSPVDILDPETQVSQECQELTLDGFETKSSNRTTM 112

  Fly    81 VNNGHSIQLSGFDHELTLSGGALLQDFVVEQIHMHW-------WSEHTINDIRYPLEVHIVHRNT 138
            .|.|.::.:. ..::..:.|..|...|..|::..||       .|||:||..::|:|:.|...|:
Zfish   113 KNTGKTVSIV-LKNDYFVRGAGLPGRFKAEKVEFHWGSTNGSAGSEHSINGKKFPVEMQIYFYNS 176

  Fly   139 -IYPNMTMAANFKDGIVVIGVLYHVSNTPNEAIGSIIKSLGAVKSYDSMNKPVLVADSLAVDDLV 202
             .:.:::.|...:..|..:.|.:.|:...|.|...||..|..|..::....    ..|..:.||:
Zfish   177 DDFDSLSTAIKERRIIAAMAVFFQVATKDNIAAEPIIAGLKRVVHHEKETN----LGSFILRDLL 237

  Fly   203 P-SVENYFTYAGSLTTPTCAEAVTWIVLTETFPV--------------TLDQVNEFKEIEYDEGK 252
            | |:.:|:.|.||||||.|::.|.||:.:.  ||              |.:|.:..|.::|
Zfish   238 PSSLGSYYRYTGSLTTPPCSKVVEWIIFSR--PVYLSYHQLEAFYSIFTTEQQDHVKSVDY---- 296

  Fly   253 QLHNNYRELQSENNRAV---VLVE--QPEQRSGSAGLTAS 287
             |.||:|.:|..::|.:   .|::  .||..:.:|....|
Zfish   297 -LRNNHRPIQDLDSRRIFKSALMDAWMPETMASAADTETS 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH7	NP_001287267.1	alpha_CA	45..269	CDD:238200	64/248 (26%)
ca16b	XP_001919055.3	alpha_CARP_receptor_like	62..314	CDD:239396	69/277 (25%)
		FN3	340..417	CDD:214495
		Herpes_BLLF1	450..>557	CDD:330317
		PTPc	790..1057	CDD:214550
		PTPc	1089..1347	CDD:214550
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810