DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH7 and CAH8

DIOPT Version :9

Sequence 1:	NP_001287267.1	Gene:	CAH7 / 41238	FlyBaseID:	FBgn0037788	Length:	304	Species:	Drosophila melanogaster
Sequence 2:	NP_001262833.1	Gene:	CAH8 / 42625	FlyBaseID:	FBgn0038956	Length:	303	Species:	Drosophila melanogaster

Alignment Length:	296	Identity:	94/296 - (31%)
Similarity:	142/296 - (47%)	Gaps:	40/296 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MHLIALS-----LIVCCSVSFSWANEWGYPDLDNNQDEPFPKWGGLCDSGKKQSPINLHVKGALK 60
            |||.||.     |:..    ..:|..:...|.|....|.:|:....| .|.:||||.:..:.|:.
  Fly     1 MHLPALDDFYQRLLFL----LPFAANFRSTDFDYKSPERWPEKYPNC-GGSEQSPIAISRRKAIP 60

  Fly    61 GEFDALKFENYDEHQKNLRMV-NNGHSIQLSGFDHELTLSG------GALLQD-FVVEQIHMHW- 116
            .....|.|..|||....|..: |:||:::   |....|:.|      |.||:| :..|.:|.||
  Fly    61 LNLPPLIFALYDEFFDELVTIRNSGHTVE---FKVPTTIYGVKPYVTGGLLRDCYDAEAVHFHWG 122

  Fly   117 -----WSEHTINDIRYPLEVHIVHRNTIYPNMTMAANFKDGIVVIGVLYHVSNTPNEAIGSIIKS 176
                 .|||.:|..|:.||:|||||||.|.|:..|..:.||:.|:.||:.|..:     |.....
  Fly   123 SPESKGSEHLLNGRRFDLEMHIVHRNTKYLNLEEAVKYSDGVTVLAVLFKVVRS-----GPFFYQ 182

  Fly   177 LGAVKSYDSM------NKPVLVADSLAVDDLVPSVE--NYFTYAGSLTTPTCAEAVTWIVLTETF 233
            .|..:.:.|:      |....|.:.|.:..|:.|::  |::||.||||||.|:..|.|.|..|..
  Fly   183 PGLSEIFSSLLHLGNFNASYTVQERLTLGSLLGSLDRGNFYTYKGSLTTPPCSPVVQWHVFGEVL 247

  Fly   234 PVTLDQVNEFKEIEYDEGKQLHNNYRELQSENNRAV 269
            |::...:.:|..:..:.|:.|..|:|.|||:.||.:
  Fly   248 PISHQDLPKFWNLRDERGRPLLKNFRPLQSQENRLI 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH7	NP_001287267.1	alpha_CA	45..269	CDD:238200	82/245 (33%)
CAH8	NP_001262833.1	Carb_anhydrase	31..281	CDD:215000	83/258 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446795
Domainoid	1	1.000	91	1.000	Domainoid score	I2610
eggNOG	1	0.900	-	-		E1_COG3338
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I2251
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG27166
OrthoDB	1	1.010	-	-		D113047at6656
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	1	1.000	-	-		mtm1014
orthoMCL	1	0.900	-	-		OOG6_100138
Panther	1	1.100	-	-	P	PTHR18952
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
	12	11.810