DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH7 and ca4c

DIOPT Version :9

Sequence 1:	NP_001287267.1	Gene:	CAH7 / 41238	FlyBaseID:	FBgn0037788	Length:	304	Species:	Drosophila melanogaster
Sequence 2:	NP_001373159.1	Gene:	ca4c / 407683	ZFINID:	ZDB-GENE-080815-6	Length:	309	Species:	Danio rerio

Alignment Length:	313	Identity:	95/313 - (30%)
Similarity:	149/313 - (47%)	Gaps:	45/313 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LIALSLIVCCSVSFSWANEWGYPD--LDNNQDEPFPKWG---GLCDSGKKQSPINLHVKGALKGE 62
            |:||.|   ||      .||.|..  ..|:..|...:|.   ..| .|:||||||:...   |.:
Zfish    11 LLALKL---CS------GEWCYQSQLSCNHTCEGPSQWKINYTSC-GGQKQSPINIITS---KVK 62

  Fly    63 FDALKFENY----DEHQKNLRMVNNGHSIQLSGFDHELTLSGGALLQDFVVEQIHMHW------W 117
            :|. |..::    .|...|:.:.|:|||...: ......||||.|...:...|.|:||      .
Zfish    63 YDP-KLTSFIFHGHEDAFNMSVENHGHSAHFT-LPPSAHLSGGGLKGKYKAVQFHLHWGENGSQG 125

  Fly   118 SEHTINDIRYPLEVHIVHRNTIYPNMTMAANFKDGIVVIGVLYHVSNTPNEAIGSIIKSLGAVKS 182
            |||:::..|||:|:|||:....|.|:|.|.....|:.|:...:.|:...|:....||::|..|:.
Zfish   126 SEHSVDGERYPMELHIVYIGEEYINLTKALQNSTGVAVLAFFFEVTALQNQKFERIIEALKKVRH 190

  Fly   183 YDSMNKPVLVADSLAVDDLVPSV--ENYFTYAGSLTTPTCAEAVTWIVLTETFPVTLDQVNEF-K 244
            .::.:|    .::..:.|::|.|  :.|:.|:||||||:|.|||.|.|..:|..::..|:... |
Zfish   191 ENTTSK----VENFKLSDIIPQVNSQKYYRYSGSLTTPSCEEAVLWTVFQQTIGISKMQMESMDK 251

  Fly   245 EIEYDEGKQLHNNYRELQSENNRAVVLVEQPEQRSGSAGLTASVSLGLMTLIL 297
            .:.:...|.:...:|.:|:.|.| ||....|..       :..|...|:||||
Zfish   252 LLLFGTDKPMAGIFRPVQNLNER-VVYTSVPAH-------SLCVLPNLLTLIL 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH7	NP_001287267.1	alpha_CA	45..269	CDD:238200	73/236 (31%)
ca4c	NP_001373159.1	alpha_CA_IV_XV_like	48..277	CDD:239391	74/238 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579125
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100138
Panther	1	1.100	-	-	O	PTHR18952
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.750