DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH7 and Ptprg

DIOPT Version :9

Sequence 1:	NP_001287267.1	Gene:	CAH7 / 41238	FlyBaseID:	FBgn0037788	Length:	304	Species:	Drosophila melanogaster
Sequence 2:	NP_599183.2	Gene:	Ptprg / 171357	RGDID:	620774	Length:	1442	Species:	Rattus norvegicus

Alignment Length:	248	Identity:	74/248 - (29%)
Similarity:	114/248 - (45%)	Gaps:	33/248 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 GKKQSPINLHVKGALKG-EFDALKFENYDEHQKNLR-MVNNGHSIQLSGFDHELTLSGGALLQDF 107
            |..||||::....|..| |:..|:.:.:|....|.. |.|.|.::.:...| :..:||..|...|
  Rat    80 GSHQSPIDILDHHARVGEEYQELQLDGFDNESSNKTWMKNTGKTVAILLKD-DYFVSGAGLPGRF 143

  Fly   108 VVEQIHMHW-------WSEHTINDIRYPLEVHIVHRN-TIYPNMTMAANFKDGIVVIGVLYHVSN 164
            ..|::..||       .|||::|..|:|:|:.|...| ..:.:...|.:....|..:.:.:.||.
  Rat   144 KAEKVEFHWGHSNGSAGSEHSVNGRRFPVEMQIFFYNPDDFDSFQTAISENRIIGAMAIFFQVSP 208

  Fly   165 TPNEAIGSIIKSLGAVKSYDSMNKPVLVADSLAVDDLVP-SVENYFTYAGSLTTPTCAEAVTWIV 228
            ..|.|:..||..|..|..::...    ..|...:.||:| |:.:|:.|.||||||.|:|.|.|||
  Rat   209 RDNSALDPIIHGLKGVVHHEKET----FLDPFVLRDLLPASLGSYYRYTGSLTTPPCSEIVEWIV 269

  Fly   229 LTETFPVTLDQVNEF------------KEIEYDEGKQLHNNYRELQSENNRAV 269
            .....|::..|:..|            |.:||     |.||:|..|:.|:|.|
  Rat   270 FRRPVPISYHQLEAFYSIFTTEQQDHVKSVEY-----LRNNFRPQQALNDRVV 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH7	NP_001287267.1	alpha_CA	45..269	CDD:238200	73/246 (30%)
Ptprg	NP_599183.2	alpha_CARP_receptor_like	67..319	CDD:239396	74/248 (30%)
		FN3	348..438	CDD:238020
		R-PTPc-G-1	845..1118	CDD:350505
		R-PTP-G-2	1202..1406	CDD:350508
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810