DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH7 and Car10

DIOPT Version :9

Sequence 1:	NP_001287267.1	Gene:	CAH7 / 41238	FlyBaseID:	FBgn0037788	Length:	304	Species:	Drosophila melanogaster
Sequence 2:	XP_017453181.1	Gene:	Car10 / 100360015	RGDID:	2322930	Length:	328	Species:	Rattus norvegicus

Alignment Length:	300	Identity:	76/300 - (25%)
Similarity:	139/300 - (46%)	Gaps:	41/300 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MHLIALSLIVCCS-------VSFSWANEWGYPDLDNNQDEPFPK-WG------GLCDSGKKQSPI 51
            :.|:..:.|||.|       :...|   |.|.::......|.|. ||      .||..||:|||:
  Rat     8 LFLLQANFIVCISAQQNSPKIHEGW---WAYKEVVQGSFVPVPSFWGLVNSAWNLCSVGKRQSPV 69

  Fly    52 NLHVKGALKGEFDALKFENYDEHQKNLRMVNNGHSIQLS-GFDHELTLSGGALLQDFVVEQIHMH 115
            |:.....:...|......|....:.:..|.|.|..:.|. ..:|.:.:|||.:.....:|:|.:|
  Rat    70 NIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLH 134

  Fly   116 W------WSEHTINDIRYPLEVHIVHRN-TIYPNMTMAANFKDGIVVIGVLYHVSNTPNEAIGSI 173
            :      .|||.:|...:..||.::|.| .:|.|:|.||...:|:||:.:...||::.|..:..:
  Rat   135 FGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRM 199

  Fly   174 IKSLGAVKSYDSMNKPVLVADS-----LAVDDLVPSVENYFTYAGSLTTPTCAEAVTWIVLTETF 233
            :       :.|::.:.....|:     |.:::|.|...::.||.||:|.|.|.|..:||::.:..
  Rat   200 L-------NRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPV 257

  Fly   234 PVTLDQVNEFKEIEYDEGKQ----LHNNYRELQSENNRAV 269
            .:|..|::..:.:..::..|    :.:|:|.:|..|||.:
  Rat   258 YITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCI 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH7	NP_001287267.1	alpha_CA	45..269	CDD:238200	62/240 (26%)
Car10	XP_017453181.1	alpha_CARP_X_XI_like	46..302	CDD:239395	67/258 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339474
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750