DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alp13 and Akp3

DIOPT Version :9

Sequence 1:	NP_649978.2	Gene:	Alp13 / 41236	FlyBaseID:	FBgn0037786	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_073171.2	Gene:	Akp3 / 64621	RGDID:	621650	Length:	558	Species:	Rattus norvegicus

Alignment Length:	512	Identity:	132/512 - (25%)
Similarity:	223/512 - (43%)	Gaps:	115/512 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LLCIGFMTRYEVENDVANVADVDYWKDKVATSQKIWYDKGIDELNEALRPQDL-TYPKNVRIFVI 99
            ||.:||  |.::...|..|.:         .:...|..|..|.||.|.:.|.: |..||:.||:.
  Rat     7 LLLLGF--RLQLSLSVIPVEE---------ENPAFWNQKAADALNVAKKLQPIQTSAKNLIIFLG 60

  Fly   100 QGIDGRDWAAFRFPTSDASR-------GN----TNFIWDRFPHLARLKN-SCSQQFPCQVASVSR 152
            .|:.        .||..|:|       ||    |....|.||::|..|. |..:|.| ..||.:.
  Rat    61 DGMG--------VPTVTATRILKGQLEGNLGPETPLAMDHFPYMALSKTYSVDRQVP-DSASTAT 116

  Fly   153 ALWLGIPLDKVPDNQQDCGRL--FNATQG--PISILRQAQLAGLRTGFVTTQRI--TGPTGAALG 211
            |...|:..:..........|.  .|.|.|  .:|::.:|:.||...|.|||.|:  ..|.|..:.
  Rat   117 AYLCGVKTNYKTIGVSAAARFDQCNTTFGNEVLSVMYRAKKAGKSVGVVTTTRVQHASPAGTYVH 181

  Fly   212 NANGNFECDESMPLNSIKSGCQDIAQQLISDETGKFLNVLIGGGRQ-MLSSLVPNTKYDPVDEML 275
            ..|.|:..|..||.::::.||:|||.||:|:..   :||::||||: |..:..|:.:| |.|  :
  Rat   182 TVNRNWYGDADMPASALQEGCKDIATQLVSNMD---INVILGGGRKYMFPAGTPDPEY-PND--V 240

  Fly   276 CESN---DGRNLLKDWRNQKLKESKINRIIFDLIQRRDELESLNSSSFDYLMGVMANGDLSGNSK 337
            .|:.   ||:||:::|    |.:.:.::.:::   |::.::.....|..||||:....|.....:
  Rat   241 NETGTRLDGKNLVQEW----LSKHQGSQYVWN---RQELIQKSLDPSVTYLMGLFEPVDTKFEIQ 298

  Fly   338 A-----PSLKLMVDKSLNVLTKYKQGYLLIVEQFIPSGIDKREQL---------QLLNDTLV--- 385
            .     ||||.|.:.:|:||::..:|:.|.||   ...||:...|         .::.|:.:
  Rat   299 RDPLMDPSLKDMTEAALHVLSRNPKGFYLFVE---GGRIDRGHHLGTAYLALTEAVMFDSAIERA 360

  Fly   386 -NLHKDQDTLTLVLM-----------------------TNAIYPKPSLDV--------------S 412
             .|..:|||||:|..                       .||:..||...:              .
  Rat   361 SQLTSEQDTLTIVTADHSHVFSFGGYTLRGTSIFGLAPLNALDGKPYTSILYGNGPGYVGTGERP 425

  Fly   413 EETETISLLPEIFNEAESEIQKRLHQMPSESLLFAQGPKSSIFQGVRKETFLAHAIS 469
            ..|:..|..|....:|...::...|. ..:..:||:||::.:..||:::.::||.::
  Rat   426 NVTDAESHDPSYQQQAAVPVKSETHG-GEDVAIFARGPQAHLLHGVQEQNYIAHVMA 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alp13	NP_649978.2	ALP_like	127..472	CDD:304875	105/409 (26%)
Akp3	NP_073171.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351427
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D216917at33208
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.850