Protein Alignment Alp13 and ALPG

DIOPT Version :10

• Sequence 1: NP_649978.2
• Gene: Alp13 / 41236
• FlyBaseID: FBgn0037786
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_112603.2
• Gene: ALPG / 251
• HGNCID: 441
• Length: 532
• Species: Homo sapiens
• Alignment Length: 484
• Identity: 125/484 - (25%)
• Similarity: 212/484 - (43%)
• Gaps: 102/484 - (21%)

  Fly    58 DYWKDKVATSQKIWYDKGIDELNEA--LRPQDLTYPKNVRIFVIQGIDGRDWAAFRF---PTSDA 117
            |:|..:.|           :.|..|  |:|.. |..||:.||:..|:......|.|.   ...|.
Human    29 DFWNRQAA-----------EALGAAKKLQPAQ-TAAKNLIIFLGDGMGVSTVTAARILKGQKKDK 81

  Fly   118 SRGNTNFIWDRFPHLARLKN-SCSQQFPCQVASVSRALWLGIPLDKVPDNQQDCG-------RLF 174
            ....|....||||::|..|. |..:..|...|:.:..|.      .|..|.|..|       ...
Human    82 LGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLC------GVKGNFQTIGLSAAARFNQC 140

  Fly   175 NATQG--PISILRQAQLAGLRTGFVTTQRI--TGPTGAALGNANGNFECDESMPLNSIKSGCQDI 235
            |.|:|  .||::.:|:.||...|.|||.|:  ..|.||.....|.|:..|..:|.::.:.|||||
Human   141 NTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDI 205

  Fly   236 AQQLISDETGKFLNVLIGGGRQMLSSL-VPNTKYDPVDEMLCESN-DGRNLLKDWRNQKLKESKI 298
            |.||||:..   ::|::||||:.:..: .|:.:| |.|.....:. ||:||:::|    |.:.:.
Human   206 ATQLISNMD---IDVILGGGRKYMFPMGTPDPEY-PDDYSQGGTRLDGKNLVQEW----LAKHQG 262

  Fly   299 NRIIFDLIQRRDELESLNSSSFDYLMGVMANGDLS-----GNSKAPSLKLMVDKSLNVLTKYKQG 358
            .|.:::   |.:.|::....|..:|||:...||:.     .::..|||..|.:.:|.:|::..:|
Human   263 ARYVWN---RTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSRNPRG 324

  Fly   359 YLLIVE-QFIPSGIDKREQLQLLNDTLV---------NLHKDQDTLTLV--------------LM 399
            :.|.|| ..|..|..:....:.|.:|::         .|..::|||:||              |.
Human   325 FFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLR 389

  Fly   400 TNAIY---PKPSLDVS---------------------EETETISLLPEIFNEAESEIQKRLHQMP 440
            .::|:   |..:.|..                     :.||:.|..||...::...:....| ..
Human   390 GSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDGETH-AG 453

  Fly   441 SESLLFAQGPKSSIFQGVRKETFLAHAIS 469
            .:..:||:||::.:..||:::||:||.::
Human   454 EDVAVFARGPQAHLVHGVQEQTFIAHVMA 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp13	NP_649978.2	ALP_like	127..472	CDD:474031	108/410 (26%)
ALPG	NP_112603.2	Alk_phosphatase	52..487	CDD:395188	117/449 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	422..443		5/20 (25%)