Protein Alignment Alp13 and ALPI

DIOPT Version :9

• Sequence 1: NP_649978.2
• Gene: Alp13 / 41236
• FlyBaseID: FBgn0037786
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_001622.2
• Gene: ALPI / 248
• HGNCID: 437
• Length: 528
• Species: Homo sapiens
• Alignment Length: 481
• Identity: 124/481 - (25%)
• Similarity: 212/481 - (44%)
• Gaps: 111/481 - (23%)

  Fly    71 WYDKGIDELNEALRPQDL-TYPKNVRIFVIQGIDGRDWAAFRFPTSDASR---GNTN-------- 123
            |..:..:.|:.|.:.|.: ...||:.:|:..|:.        .||..|:|   |..|
Human    31 WNRQAAEALDAAKKLQPIQKVAKNLILFLGDGLG--------VPTVTATRILKGQKNGKLGPETP 87

  Fly   124 FIWDRFPHLARLKN-SCSQQFPCQVASVSRALWLGIPLDKVPDNQQDCG-------RLFNATQG- 179
            ...||||:||..|. :..:|.|...|:.:..|.      .|..|.|..|       ...|.|:|
Human    88 LAMDRFPYLALSKTYNVDRQVPDSAATATAYLC------GVKANFQTIGLSAAARFNQCNTTRGN 146

  Fly   180 -PISILRQAQLAGLRTGFVTTQRI--TGPTGAALGNANGNFECDESMPLNSIKSGCQDIAQQLIS 241
             .||::.:|:.||...|.|||.|:  ..|.|......|.|:..|..||.::.:.||||||.||||
Human   147 EVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADMPASARQEGCQDIATQLIS 211

  Fly   242 DETGKFLNVLIGGGRQMLSSL-VPNTKYDPVDEMLCESN----DGRNLLKDWRNQKLKESKINRI 301
            :..   ::|::||||:.:..: .|:.:| |.|   ...|    ||:||:::|..:       ::.
Human   212 NMD---IDVILGGGRKYMFPMGTPDPEY-PAD---ASQNGIRLDGKNLVQEWLAK-------HQG 262

  Fly   302 IFDLIQRRDELESLNSSSFDYLMGVMANGDLS-----GNSKAPSLKLMVDKSLNVLTKYKQGYLL 361
            .:.:..|.:.:::....|..:|||:...||..     ..:..|||..|.:.:|.:|::..:|:.|
Human   263 AWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRDPTLDPSLMEMTEAALRLLSRNPRGFYL 327

  Fly   362 IVE-QFIPSGIDKREQLQLLNDTLV---------NLHKDQDTLTLV--------------LMTNA 402
            .|| ..|..|..:....|.|.:.::         .|..::||||||              |..::
Human   328 FVEGGRIDHGHHEGVAYQALTEAVMFDDAIERAGQLTSEEDTLTLVTADHSHVFSFGGYTLRGSS 392

  Fly   403 IY---PKPSLDVSEETETI-----------SLLPEIFNEAESEI----QKRLHQMPSES------ 443
            |:   |..:.|....|..:           .:.|:: ||:||..    |:....:.||:
Human   393 IFGLAPSKAQDSKAYTSILYGNGPGYVFNSGVRPDV-NESESGSPDYQQQAAVPLSSETHGGEDV 456

  Fly   444 LLFAQGPKSSIFQGVRKETFLAHAIS 469
            .:||:||::.:..||::::|:||.::
Human   457 AVFARGPQAHLVHGVQEQSFVAHVMA 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp13	NP_649978.2	ALP_like	127..472	CDD:304875	110/413 (27%)
ALPI	NP_001622.2	Alk_phosphatase	52..487	CDD:306706	120/460 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157470
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1785
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D216917at33208
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	6	5.710