Protein Alignment nerfin-2 and ZNF99

DIOPT Version :10

• Sequence 1: NP_001262446.1
• Gene: nerfin-2 / 41235
• FlyBaseID: FBgn0041105
• Length: 775
• Species: Drosophila melanogaster
• Sequence 2: NP_001073878.2
• Gene: ZNF99 / 7652
• HGNCID: 13175
• Length: 864
• Species: Homo sapiens
• Alignment Length: 239
• Identity: 62/239 - (25%)
• Similarity: 89/239 - (37%)
• Gaps: 61/239 - (25%)

  Fly   386 KAERRRSKLRKHMAID--------EETISPVSGTIIRKLRDDEELVVRKG-------DIDPAF-- 433
            ||.:|.|.||||..|.        ||.....|.  ...||..|  ::..|       :...||
Human   432 KAFKRFSALRKHKIIHTGKQPYKCEECSKAFSN--FSALRKHE--IIHTGEKPYKCEECGKAFKW 492

  Fly   434 -------NVVEITEEAKAILASIDNKIGDYMCQLCRTVYDDAFMLAQHRCPRIVHI---EYKCSE 488
                   .|:.:.|:             ...|:.|...:.....|.:|   :|:|.   .|||.|
Human   493 SSKLTVHKVIHMEEK-------------PCKCEECGKAFKHFSALRKH---KIIHTGKKPYKCEE 541

  Fly   489 CEKVFNCPANLASHRRWH---KP-KAEAAGVNPAKKRVVETGDLVQ-EATRSGDDASDGIYPCHI 548
            |.|.||..:.|..|:..|   || |.|..|     |...::..|.: :|..:|:..    |.|..
Human   542 CGKAFNNSSTLMKHKIIHTGKKPYKCEECG-----KAFKQSSHLTRHKAIHTGEKP----YKCEE 597

  Fly   549 CGKTFRRQAYLKKHQASHQMLDNLKNLDFFKSQQQQLTINGHQL 592
            |||.|...:.|:|||..|......|..:..|:..|..|:..|::
Human   598 CGKAFNHFSALRKHQIIHTGKKPYKCEECGKAFSQSSTLRKHEI 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nerfin-2	NP_001262446.1	C2H2 Zn finger	458..481	CDD:275368	5/22 (23%)
		C2H2 Zn finger	486..506	CDD:275368	8/19 (42%)
		zf-C2H2	544..566	CDD:395048	10/21 (48%)
		C2H2 Zn finger	546..566	CDD:275368	9/19 (47%)
ZNF99	NP_001073878.2	KRAB	4..64	CDD:214630
		C2H2 Zn finger	147..167	CDD:275368
		C2H2 Zn finger	175..195	CDD:275368
		C2H2 Zn finger	203..223	CDD:275368
		C2H2 Zn finger	232..251	CDD:275368
		C2H2 Zn finger	259..279	CDD:275368
		COG5048	267..684	CDD:227381	62/239 (26%)
		C2H2 Zn finger	287..307	CDD:275368
		C2H2 Zn finger	315..335	CDD:275368
		C2H2 Zn finger	343..363	CDD:275368
		C2H2 Zn finger	371..391	CDD:275368
		C2H2 Zn finger	399..419	CDD:275368
		C2H2 Zn finger	427..447	CDD:275368	8/14 (57%)
		C2H2 Zn finger	455..475	CDD:275368	6/23 (26%)
		C2H2 Zn finger	483..503	CDD:275368	3/19 (16%)
		C2H2 Zn finger	511..531	CDD:275368	5/22 (23%)
		COG5048	534..857	CDD:227381	36/117 (31%)
		C2H2 Zn finger	539..559	CDD:275368	8/19 (42%)
		C2H2 Zn finger	567..587	CDD:275368	5/24 (21%)
		C2H2 Zn finger	595..615	CDD:275368	9/19 (47%)
		C2H2 Zn finger	623..643	CDD:275368	4/19 (21%)
		C2H2 Zn finger	651..671	CDD:275368
		C2H2 Zn finger	679..699	CDD:275368
		C2H2 Zn finger	707..727	CDD:275368
		C2H2 Zn finger	735..755	CDD:275368
		C2H2 Zn finger	763..783	CDD:275368
		C2H2 Zn finger	791..811	CDD:275368
		C2H2 Zn finger	819..839	CDD:275368