Protein Alignment nerfin-2 and nerfin-1

DIOPT Version :10

• Sequence 1: NP_001262446.1
• Gene: nerfin-2 / 41235
• FlyBaseID: FBgn0041105
• Length: 775
• Species: Drosophila melanogaster
• Sequence 2: XP_003436169.1
• Gene: nerfin-1 / 3290645
• VectorBaseID: AGAMI1_013015
• Length: 526
• Species: Anopheles gambiae
• Alignment Length: 540
• Identity: 157/540 - (29%)
• Similarity: 207/540 - (38%)
• Gaps: 178/540 - (32%)

  Fly   316 PEPDVEVSGLAELQSNSGKTYTDLSG------------VATAEIRTTS----SDNLPPPPPPPP- 363
            |.|...::.:|.|..:....|.:::|            :...::.||:    :..:.||..|.|
Mosquito    13 PSPAGLLTTVASLPPSYKLQYDEVAGRPVPATGDSPLDLTVRQVTTTTTTVVTGPITPPATPSPL 77

  Fly   364 ------------------PPATSTIPATPPL------------------------PP-----PPI 381
                              |.|....||..||                        ||     ||.
Mosquito    78 KKRYREDNQLNVPAVKEEPLAKRAKPAPEPLHIDIKKELATPAKTASPKGGQPDGPPKSTKNPPA 142

  Fly   382 SRPHKAERRRSKLRKHMAIDEETISPVSGTIIRKLRD--DEELVVRKGDIDPAFNVVEITEEAKA 444
            :.....|||...:|| :..|||..||||||||..|.:  ..:.....|||||.||:||:::|.:|
Mosquito   143 ALAPSKERRAKAIRK-LKFDEENSSPVSGTIIISLEEALSGDTPRESGDIDPQFNLVEVSDEVRA 206

  Fly   445 ILASIDNKIGDYMCQLCRTVYDDAFMLAQHRCPRIVHIEYKCSECEKVFNCPANLASHRRWHKPK 509
            .||:|.|.||.|.|:|||..::|||.||||||..||.:||:|.||.|.||||||||||||||||:
Mosquito   207 ELAAIPNVIGGYNCKLCRLEFEDAFGLAQHRCSCIVLLEYRCPECGKRFNCPANLASHRRWHKPR 271

  Fly   510 AEAAGVNPAKKRVVETGDLVQEATRSGDD-------ASDGIYPCHICGKTFRRQAYLKKHQASHQ 567
            .:.     .||..|........|..|.|.       |..|.:.|..|.|||:|.|||||||.:|
Mosquito   272 DQV-----GKKGGVAAAAAATRAEPSSDSTDSDSGGAQAGKFRCVQCDKTFKRPAYLKKHQLTH- 330

  Fly   568 MLDNLKNLDFFKSQQQQLTINGHQLADHVQLQHTTGQAVTSAAPYASLPRPPPGMPMYPPPSGKN 632
                         .:|..:..|             |:..|...|          .|..|.||...
Mosquito   331 -------------SRQAASKQG-------------GKGATKQQP----------RPASPSPSTAQ 359

  Fly   633 YPGGQRFPGFPFQSFDQRRFYSLGEFYLSQHLERSSAFQYVQANHLRQLSNVAQT-LMPPLPVKX 696
            |           :|.|            |.|...||  |.|::......::..|: ::|..|
Mosquito   360 Y-----------RSED------------SNHSNHSS--QSVESGTATYTADSRQSQVVPQAP--- 396

  Fly   697 PNPNTNVLRPVPRIAATATATGPPAAATATRQAATAAGVSSVGHAFNWVAPSTAGATATGSATAT 761
                                  ||.|...|  .|:..||....|.|..|   .|.....|.||.|
Mosquito   397 ----------------------PPLAMFTT--LASDDGVGGGEHEFEVV---NAAGYYQGPATVT 434

  Fly   762 -----ATATTAESG-GNVIM 775
                 |.:..:.|| |:|.:
Mosquito   435 FVRERAPSVASSSGRGSVAL 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nerfin-2	NP_001262446.1	C2H2 Zn finger	458..481	CDD:275368	14/22 (64%)
		C2H2 Zn finger	486..506	CDD:275368	16/19 (84%)
		zf-C2H2	544..566	CDD:395048	13/21 (62%)
		C2H2 Zn finger	546..566	CDD:275368	13/19 (68%)
nerfin-1	XP_003436169.1	SUF4-like	220..>269	CDD:411020	34/48 (71%)
		C2H2 Zn finger	220..240	CDD:275368	13/19 (68%)
		zf-C2H2	246..268	CDD:395048	17/21 (81%)
		C2H2 Zn finger	248..268	CDD:411020	16/19 (84%)
		C2H2 Zn finger	248..268	CDD:275368	16/19 (84%)
		zf-C2H2	308..330	CDD:395048	13/21 (62%)
		C2H2 Zn finger	310..330	CDD:275368	13/19 (68%)