DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nerfin-2 and F26F4.8

DIOPT Version :9

Sequence 1:	NP_001262446.1	Gene:	nerfin-2 / 41235	FlyBaseID:	FBgn0041105	Length:	775	Species:	Drosophila melanogaster
Sequence 2:	NP_001379726.1	Gene:	F26F4.8 / 184991	WormBaseID:	WBGene00005011	Length:	302	Species:	Caenorhabditis elegans

Alignment Length:	165	Identity:	39/165 - (23%)
Similarity:	62/165 - (37%)	Gaps:	38/165 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   441 EAKAILASIDNKIGDYMCQLCRTVYDDAFMLAQH--RCPRIVHIE--YKCSECEKVFNCPANLAS 501
            |..|...|.|.|:   .|:.|     |.|..::.  ||...||.:  .:|..|:|:||....|..
Worm    12 EVNANTTSPDVKV---KCKQC-----DRFFTSERSLRCHIKVHNDKLLECYFCDKMFNRTDTLFF 68

  Fly   502 HRRWHKPKAEAAGVNPAKKRVVETGDLVQEATRSGDDASDGIY--------PCHICGK---TFRR 555
            |...|..|    |..|.:   .|..|.:.|....|::.::..:        .|..|.:   :||:
Worm    69 HALDHISK----GTLPCR---AEGCDQLVETMLEGENHANTAHHVNGTVSIKCKDCSEVSVSFRK 126

  Fly   556 QAYLKKHQASHQMLDN------LKNLDFFKSQQQQ 584
            ..:  .|...|..|..      :|..||.:.::.|
Worm   127 MLF--HHTFKHGELKEYAEEMIIKQKDFLRMKKNQ 159

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nerfin-2	NP_001262446.1	C2H2 Zn finger	458..481	CDD:275368	6/24 (25%)
		C2H2 Zn finger	486..506	CDD:275368	7/19 (37%)
		zf-C2H2	544..566	CDD:278523	5/32 (16%)
		C2H2 Zn finger	546..566	CDD:275368	5/22 (23%)
F26F4.8	NP_001379726.1	C2H2 Zn finger	26..46	CDD:275368	6/24 (25%)
F26F4.8	NP_001379726.1	C2H2 Zn finger	53..73	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S8156
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950