DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Npc2c and heh-1

DIOPT Version :9

Sequence 1:	NP_649976.1	Gene:	Npc2c / 41233	FlyBaseID:	FBgn0037783	Length:	165	Species:	Drosophila melanogaster
Sequence 2:	NP_001379800.1	Gene:	heh-1 / 175426	WormBaseID:	WBGene00006452	Length:	154	Species:	Caenorhabditis elegans

Alignment Length:	158	Identity:	39/158 - (24%)
Similarity:	70/158 - (44%)	Gaps:	20/158 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LVLSIMWTSVADSTPI--RQC-ADSNYPQPLMVQIDDCDAL------PCDLWKGTEAKIDIQFVA 66
            :.|:::..:.|:...|  :.| :|....|   |:.|.|:..      .|...||:...|.|.|..
Worm     5 IFLALLGLAAAEFIEIGYKVCKSDGTVSQ---VKADGCELTVKDGKKVCLFKKGSRPIIQIAFKP 66

  Fly    67 TRNTMKKLSAEVHLTSLGVTIPYDLEASRGNVCSNLLHGAYCPLDAGEDVTYQLLLPVTTNQP-- 129
            :::| .||...|. ..:|.:...|...:..:.|:   :|..||:.|||:..::..:.:|.|.|
Worm    67 SKDT-DKLKTSVR-AKVGGSAMVDFPQTNSDACT---YGVKCPVSAGENQIFEQSISITENHPAG 126

  Fly   130 EVPTRLEVRLLDSDDENRVVSCFLADTR 157
            || .::..:|...|....|...|||:.:
Worm   127 EV-IQVNWQLTRPDSGKEVCIIFLAEIK 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Npc2c	NP_649976.1	Npc2_like	26..155	CDD:238458	36/139 (26%)
heh-1	NP_001379800.1	Npc2_like	22..150	CDD:238458	34/136 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4063
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1612792at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11306
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920