Protein Alignment Npc2c and NPC2

DIOPT Version :9

• Sequence 1: NP_649976.1
• Gene: Npc2c / 41233
• FlyBaseID: FBgn0037783
• Length: 165
• Species: Drosophila melanogaster
• Sequence 2: NP_001350617.1
• Gene: NPC2 / 10577
• HGNCID: 14537
• Length: 174
• Species: Homo sapiens
• Alignment Length: 147
• Identity: 42/147 - (28%)
• Similarity: 68/147 - (46%)
• Gaps: 19/147 - (12%)

  Fly    11 LVLSIMWTSVADSTPIRQC--ADSNYPQPLMVQIDDCDALPCDLWKGTEAKIDIQFVATRNTMKK 73
            |:|::...:.|:....:.|  .|....:   |.:..|...||.|.||....:::.|  |.|...|
Human     9 LLLALSTAAQAEPVQFKDCGSVDGVIKE---VNVSPCPTQPCQLSKGQSYSVNVTF--TSNIQSK 68

  Fly    74 LS-AEVHLTSLGVTIPYDLEASRGNVCSNLLHGAYCPLDAGEDVTYQLL--LPVTTNQPEVPTRL 135
            .| |.||...:||.:|:.:....|  |.:   |..||:.  :|.||..|  |||.:..|.:...:
Human    69 SSKAVVHGILMGVPVPFPIPEPDG--CKS---GINCPIQ--KDKTYSYLNKLPVKSEYPSIKLVV 126

  Fly   136 EVRLLDSDDENRVVSCF 152
            |.:|  .||:|:.:.|:
Human   127 EWQL--QDDKNQSLFCW 141

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Npc2c	NP_649976.1	Npc2_like	26..155	CDD:238458	39/132 (30%)
NPC2	NP_001350617.1	Npc2_like	24..145	CDD:238458	39/132 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4063
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1612792at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11306
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	6	5.880