DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Npc2d and npc2.2

DIOPT Version :9

Sequence 1:	NP_649975.1	Gene:	Npc2d / 41232	FlyBaseID:	FBgn0037782	Length:	173	Species:	Drosophila melanogaster
Sequence 2:	NP_001122191.1	Gene:	npc2.2 / 565099	ZFINID:	ZDB-GENE-080723-11	Length:	149	Species:	Danio rerio

Alignment Length:	161	Identity:	40/161 - (24%)
Similarity:	68/161 - (42%)	Gaps:	16/161 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEVKVLVLISLGLLLSLAEAQQEHPATSVK--KCSGSKPFPLEVRVHNCVTPPCQIVKGTTQKFE 63
            |:.:||.:|.|..|....       |..||  .|.......::|.:..|...|||:.||.:....
Zfish     1 MDYRVLAVILLSFLAYTC-------ADPVKFVDCGSVHGKVVQVDIKPCSQQPCQLHKGQSYTVN 58

  Fly    64 IDFAVDKYITQLTTLVKATTLGIITVPYELPADVAAVCPNLQYGAYCPLYPTEDVSYLFTFPI-G 127
            :.| :....:|.:..|....:..:.||:.:|.|     ...:.|..||:.|.:..:|:...|: .
Zfish    59 VTF-ISSVASQTSKAVVHGVVECVPVPFPIPID-----DGCKSGIQCPIVPQKPYNYVTELPVKT 117

  Fly   128 EYPEIGVKIEIYLVDQDNEIATCFVCDIKVV 158
            |||.|.|.:|..|.|..::...|....:::|
Zfish   118 EYPAIKVVVEWELRDDSSKDLFCIKFPVQIV 148

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Npc2d	NP_649975.1	Npc2_like	29..155	CDD:238458	32/128 (25%)
npc2.2	NP_001122191.1	Npc2_like	24..145	CDD:238458	30/126 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4063
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1612792at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11306
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.920