Protein Alignment Fancl and fancl

DIOPT Version :9

• Sequence 1: NP_649974.1
• Gene: Fancl / 41231
• FlyBaseID: FBgn0037781
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: NP_998147.1
• Gene: fancl / 406255
• ZFINID: ZDB-GENE-040426-1045
• Length: 371
• Species: Danio rerio
• Alignment Length: 352
• Identity: 80/352 - (22%)
• Similarity: 148/352 - (42%)
• Gaps: 61/352 - (17%)

  Fly    40 WRRLKLYLPHHPALHGFQLYVQESLEYKLYTSANLKLQDDWLLE--DFLDHLPKILPAQKAPTVP 102
            |:..:|       |||:|..|::.|::.....|       ::||  ..|:...|..|..::.:.|
Zfish    54 WQMKRL-------LHGYQHIVKQRLQHSTTLMA-------FILELRTVLEVALKSQPGCQSFSPP 104

  Fly   103 K---ELCREGNIY-YDILALYKSNEYCLQVDEACSMIRFSEFTDFEQHYLELKIPSL-------L 156
            :   :|..|..|. :|.|....:....||:.        :|.:...||.:.:|:.|.       .
Zfish   105 QYYSQLITEMEILGWDKLLFIDAEFRTLQLK--------AEDSAGRQHAITVKLKSKYPAEAPEF 161

  Fly   157 LLDHSLPDCVSLGEMLTKSAGNLEEALNLFRKLLEDLRPFYDNFMDIDELCHVLQPSPISSKHKT 221
            ..|..:|..::.....|.:..:.:..||     :|.|..|:....:|||...||:|...:....|
Zfish   162 SADLPIPLVITWTSQSTLANVHSQFLLN-----VEALSDFWSVLDEIDEKTWVLEPEKPTKADST 221

  Fly   222 RLFPLKDRVYLKLTIAD------PFACIASMSLKIIGPTEEVARLRHVLSDGLSNWDSEMNIHKN 280
            |...:.:.|.:|:.|..      |..|       ::|....|..||:.|:..:..|:.:..:.:|
Zfish   222 RRIAIGNNVSIKVQIDPRHPKMLPECC-------LLGAEHVVTPLRNKLNANMHLWNPDCTVLQN 279

  Fly   281 LLRMFDLCYFPMPDWSDGPKLDEEDNEELRCNICFAYRLDGGEVPLVSCDNAKCVLKCHAVCLEE 345
            :..:.:: .||      .|...|:.:..:.|.||::|||:.. :|...|::.:|....|.|||.|
Zfish   280 MKDVLEI-EFP------SPTTHEKSSFSVECGICYSYRLESA-IPDQVCNDPRCGQPFHQVCLYE 336

  Fly   346 WFKTLMDGKTFLEVSFGQCPFCKAKLS 372
            |.:.|...:....:.||:||:|...::
Zfish   337 WLRGLPTSRQSFNIVFGECPYCSKPIT 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fancl	NP_649974.1	WD-3	20..293	CDD:286806	57/271 (21%)
		FANCL_C	307..376	CDD:288626	21/66 (32%)
fancl	NP_998147.1	WD-3	12..291	CDD:286806	57/277 (21%)
		FANCL_C	299..366	CDD:288626	21/66 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587270
Domainoid	1	1.000	54	1.000	Domainoid score	I11182
eggNOG	1	0.900	-	-		E1_KOG3268
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	78	1.000	Inparanoid score	I5234
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1002812at2759
OrthoFinder	1	1.000	-	-		FOG0007502
OrthoInspector	1	1.000	-	-		oto40050
orthoMCL	1	0.900	-	-		OOG6_105411
Panther	1	1.100	-	-	LDO	PTHR13206
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5262
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.790