DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fancl and Fancl

DIOPT Version :10

Sequence 1:NP_649974.1 Gene:Fancl / 41231 FlyBaseID:FBgn0037781 Length:381 Species:Drosophila melanogaster
Sequence 2:XP_006251659.3 Gene:Fancl / 305600 RGDID:1311427 Length:467 Species:Rattus norvegicus


Alignment Length:370 Identity:83/370 - (22%)
Similarity:132/370 - (35%) Gaps:96/370 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    70 TSANLKLQDDWLLEDFLDHLPKILPAQKAPTVPKE-LCREGNIYYDILALYKS------------ 121
            |.|||           |.|.|.:||..:..||.:. :..:|..::..:.|.|.            
  Rat   119 TEANL-----------LRHFPLLLPQNREKTVYEGFISAQGRDFHLRIVLPKDQQLKKARLLCSW 172

  Fly   122 ------NEYCLQVDEACSMIRFSEFTDFEQHYLELKIPSLLLLDHSL----------PDCVSLGE 170
                  |||...|.:     |.....|.....:||||    :|:.:|          |.|....:
  Rat   173 QLKNILNEYHQVVQQ-----RMKHSPDLMSFMMELKI----ILEAALKNKQELYVQPPSCSFCKD 228

  Fly   171 MLT--------------------------------------KSAGNLEEALNLFRKLLEDLRPFY 197
            :||                                      |:..:|....:.|...||.|:.|:
  Rat   229 LLTEIGAIGWDKLACVDTSFTTIKLKADDASGRKHLITVKLKAKSSLVNVYSQFSAALETLKAFW 293

  Fly   198 DNFMDIDELCHVLQPSPISSKHKTRLFPLKDRVYLKLTIADPFACIASMSLKIIGPTEEVARLRH 262
            |...:|||...||:|.........|...|...|.:.:.: ||...........:|.......|..
  Rat   294 DVMDEIDEKTWVLEPEKPPRSATARRIALGHDVSINIEV-DPRHPTMLPEFCFLGADHVTKPLGM 357

  Fly   263 VLSDGLSNWDSEMNIHKNLLRMFDLCYFPMPDWSDGPKLDEEDNEELRCNICFAYRLDGGEVPLV 327
            .||..:..||.|.::.:||..:.::      |:.....|::.| ..:.|.||:|..|:|. :|..
  Rat   358 RLSGNIHLWDPENSLLQNLKDVLEI------DFPARTVLEKSD-FSMDCGICYARHLNGA-IPDQ 414

  Fly   328 SCDNAKCVLKCHAVCLEEWFKTLMDGKTFLEVSFGQCPFCKAKLS 372
            .|:|.:|....|.:||.||.:.|...:....|.||:||:|...::
  Rat   415 VCNNPQCGQLFHQMCLYEWLRGLSSSRQSFNVFFGECPYCSKPIT 459

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FanclNP_649974.1 FANCL_d1 8..95 CDD:462888 8/24 (33%)
DRWD-N_DmFANCL 108..186 CDD:467643 21/143 (15%)
DRWD-C_DmFANCL 194..292 CDD:467647 22/97 (23%)
FANCL_C 307..376 CDD:463350 22/66 (33%)
FanclXP_006251659.3 None

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