DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fancl and Y105C5B.11

DIOPT Version :9

Sequence 1:	NP_649974.1	Gene:	Fancl / 41231	FlyBaseID:	FBgn0037781	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_001263827.1	Gene:	Y105C5B.11 / 190893	WormBaseID:	WBGene00013651	Length:	772	Species:	Caenorhabditis elegans

Alignment Length:	267	Identity:	49/267 - (18%)
Similarity:	91/267 - (34%)	Gaps:	97/267 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 ESLEYKLYTSANLKLQDDWLLEDFLDHLPKILPAQKAPTVPKELCREGNIY-------YDILALY 119
            ||.|||              .:|.:.:..|:|.::|.      :|.:|.:.       ..:::||
Worm    55 ESKEYK--------------RKDVVLYREKLLISEKL------ICLDGQVLTVSCAVAAMLVSLY 99

  Fly   120 KSNEYCLQVDEACSMIR---FSEFTDFEQHYLELK--------IPSLLLLD----------HSLP 163
            .........|:..|.:|   ..:..::...||.:|        :..|:.:|          |.||
Worm   100 VERHQHKLTDKQISKLRKYMMLKNIEYRPFYLNIKDMRWIYDNVDFLMNIDKDTLRPLDNRHQLP 164

  Fly   164 DCVSLGEMLTKSAGNLEEALNLFRKLLEDL--------RPFYDNFMDIDELCHVLQPSPISSKHK 220
            :...|.|:         ..|:::.:.:...        |.|.::.:||..:....|.:||:...|
Worm   165 NITELAEL---------HQLDVYLRTVTSTLINPDAHRRIFVEDLLDIIPILLKQQGNPINEAGK 220

  Fly   221 TRLFPLKDRVYL---------------------------KLTIADPFACIASMSLKIIGPTEEVA 258
            .::  .|.||.|                           |||:|.....:.|....::.|.::..
Worm   221 QKI--RKYRVELQGDIAGHSTVDLKKLDEILDDFDVDKTKLTLAPEVTNLVSREQMMMHPRDQYL 283

  Fly   259 RLRHVLS 265
               ||||
Worm   284 ---HVLS 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fancl	NP_649974.1	WD-3	20..293	CDD:286806	49/267 (18%)
Fancl	NP_649974.1	FANCL_C	307..376	CDD:288626
Y105C5B.11	NP_001263827.1	OmpH	610..>678	CDD:377167
		RING_Ubox	716..758	CDD:388418
		RING-H2 finger (C3H2C3-type)	717..758	CDD:319361
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D411664at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010