| Sequence 1: | NP_649973.1 | Gene: | ohgt / 41230 | FlyBaseID: | FBgn0037780 | Length: | 585 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_057386.2 | Gene: | CRBN / 51185 | HGNCID: | 30185 | Length: | 442 | Species: | Homo sapiens |
| Alignment Length: | 419 | Identity: | 118/419 - (28%) |
|---|---|---|---|
| Similarity: | 197/419 - (47%) | Gaps: | 54/419 - (12%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 170 SQEAAEQPVDPPPQQPPRPPIDIGFDTNLPAEHSYFGNHLSRVPG-----VDYLEVGSVHHMLIF 229
Fly 230 LHQHILFPGEVLPFMIDGRMFDEDMPGLDGLI-----FGV-SFPRLQPPEDNPHKLYGVTCQIYE 288
Fly 289 -RGESGRGLVFYKSRALQRIVINCDDIKGSPQYIARNPTSKCFSKVKILPEYFLPEPLQTVDMGS 352
Fly 353 MARFRDIPSMR------------DKY--RRFQLST-TTWPSDACQEYSFSSIVERARQRL----E 398
Fly 399 SQKIDTMPKCPIQLSFWLVRNLHLTEKMMRLTFL-TDSVNTRLQLIKSTFKDETLFFCRYC-NSS 461
Fly 462 LALCSDLFAMSKHGVQTQYCNPEGYIHETNTVYRVISHAIGYSGEPSTKFSWFPGYQWHIILCKF 526
Fly 527 CAQHVGWEFKAVHPNLTPKVFFGLAGSSV 555 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| ohgt | NP_649973.1 | PHA02664 | <35..109 | CDD:177447 | |
| CRBN_C_like | 453..555 | CDD:276940 | 41/102 (40%) | ||
| CRBN | NP_057386.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..45 | 4/19 (21%) | |
| LON_substr_bdg | 80..317 | CDD:308028 | 60/255 (24%) | ||
| CRBN_C_like | 321..422 | CDD:276940 | 41/102 (40%) | ||
| Thalidomide binding. /evidence=ECO:0000269|PubMed:25108355, ECO:0007744|PDB:4TZ4 | 378..386 | 6/7 (86%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165145841 | |
| Domainoid | 1 | 1.000 | 97 | 1.000 | Domainoid score | I7309 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG1400 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 151 | 1.000 | Inparanoid score | I4379 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG59385 | |
| OrthoDB | 1 | 1.010 | - | - | D1069900at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0004987 | |
| OrthoInspector | 1 | 1.000 | - | - | oto90389 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_104695 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR14255 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3865 |
| SonicParanoid | 1 | 1.000 | - | - | X4635 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 15 | 14.800 | |||||