DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11722 and NDUFAF4

DIOPT Version :9

Sequence 1:	NP_649970.1	Gene:	CG11722 / 41227	FlyBaseID:	FBgn0037777	Length:	203	Species:	Drosophila melanogaster
Sequence 2:	NP_054884.1	Gene:	NDUFAF4 / 29078	HGNCID:	21034	Length:	175	Species:	Homo sapiens

Alignment Length:	176	Identity:	60/176 - (34%)
Similarity:	95/176 - (53%)	Gaps:	11/176 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SMVARRANRFNVENRAHRVLEREKPTPAPKFDSNLRDMERTLELDPKFVDKLNMKDSSLDGRLKD 70
            ::|.|....||:||||.|.:.:.||:.||:..|....:...:.|.|:...::..||..|...|||
Human     3 ALVIRGIRNFNLENRAEREISKMKPSVAPRHPSTNSLLREQISLYPEVKGEIARKDEKLLSFLKD 67

  Fly    71 VYVTSQDRFIKRVQERQAAEAAADNVEQRPLPLERKTPDDFEYGYLEPNRISPGHCTLRQALKFI 135
            |||.|:|. :..:|.: |||...:       |.|.:.|.|..:..:....|..|..::.:||..:
Human    68 VYVDSKDP-VSSLQVK-AAETCQE-------PKEFRLPKDHHFDMINIKSIPKGKISIVEALTLL 123

  Fly   136 NDHQLDPESWPAKKIANEYKLKEPLVENILHYFKTFNMYI--PDQK 179
            |:|:|.||:|.|:||..||:|::..|.::|.||.||.:.|  |:.|
Human   124 NNHKLFPETWTAEKIMQEYQLEQKDVNSLLKYFVTFEVEIFPPEDK 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11722	NP_649970.1	UPF0240	1..178	CDD:284252	59/173 (34%)
NDUFAF4	NP_054884.1	UPF0240	2..167	CDD:369079	58/172 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155334
Domainoid	1	1.000	96	1.000	Domainoid score	I7371
eggNOG	1	0.900	-	-		E1_KOG4481
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40928
Inparanoid	1	1.050	96	1.000	Inparanoid score	I5051
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45530
OrthoDB	1	1.010	-	-		D1395543at2759
OrthoFinder	1	1.000	-	-		FOG0007490
OrthoInspector	1	1.000	-	-		oto91342
orthoMCL	1	0.900	-	-		OOG6_109656
Panther	1	1.100	-	-	LDO	PTHR13338
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4682
SonicParanoid	1	1.000	-	-		X5615
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800