DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3909 and SKI8

DIOPT Version :9

Sequence 1:NP_649969.1 Gene:CG3909 / 41226 FlyBaseID:FBgn0027524 Length:331 Species:Drosophila melanogaster
Sequence 2:NP_011302.1 Gene:SKI8 / 852659 SGDID:S000003181 Length:397 Species:Saccharomyces cerevisiae


Alignment Length:311 Identity:70/311 - (22%)
Similarity:125/311 - (40%) Gaps:67/311 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    54 FLVTGGLDDLVKVWD---LQEDNT-----LKLRHKLKGHALGVVSVAVSSDG---QTIASSSLDS 107
            |.|:...|..:||||   |..:|.     ....||...|.:.|:. |:..|.   ..:|::|...
Yeast    28 FTVSCSGDGYLKVWDNKLLDNENPKDKSYSHFVHKSGLHHVDVLQ-AIERDAFELCLVATTSFSG 91

  Fly   108 TMCLWDARSGDKKHLLSFGPVDL----------WTVQFSPCNKYVISG---LNDGKISMY----- 154
            .:..:.....|:...:.|..:||          |.:::...|..::|.   ..|.|.:.|     
Yeast    92 DLLFYRITREDETKKVIFEKLDLLDSDMKKHSFWALKWGASNDRLLSHRLVATDVKGTTYIWKFH 156

  Fly   155 ------SVETGKAEQTLDAQN--------GKYTLSIAYSPDGKYIASGAIDGIITIFDVAAGKVV 205
                  :..|.....||:.|.        .::..|:..|..| .||:|..:|.:.|.:::..:.:
Yeast   157 PFADESNSLTLNWSPTLELQGTVESPMTPSQFATSVDISERG-LIATGFNNGTVQISELSTLRPL 220

  Fly   206 QTLEG-HAM-----PVRSLCFSPNSQLLLTASDD---GHMKLYDVTHSDVVGTLS---------- 251
            ...|. |:|     .:||:.|||...||..|.|.   |.:.||:....:.:|:||          
Yeast   221 YNFESQHSMINNSNSIRSVKFSPQGSLLAIAHDSNSFGCITLYETEFGERIGSLSVPTHSSQASL 285

  Fly   252 ---GHASWVLCVAFSEDGKHFASSSSDNSVKIWDTSERKCLHTFAEHTDQV 299
               .|:|||:.::|::.|:...|:..|..::.||...::.:.|...|.|.:
Yeast   286 GEFAHSSWVMSLSFNDSGETLCSAGWDGKLRFWDVKTKERITTLNMHCDDI 336

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3909NP_649969.1 WD40 52..323 CDD:238121 70/311 (23%)
WD40 <54..326 CDD:225201 70/311 (23%)
WD40 repeat 89..127 CDD:293791 6/40 (15%)
WD40 repeat 130..166 CDD:293791 9/59 (15%)
WD40 repeat 174..209 CDD:293791 8/34 (24%)
WD40 repeat 215..251 CDD:293791 13/38 (34%)
WD40 repeat 257..293 CDD:293791 8/35 (23%)
WD40 repeat 299..323 CDD:293791 0/1 (0%)
SKI8NP_011302.1 WD40 13..351 CDD:421866 70/311 (23%)
WD40 repeat 19..60 CDD:293791 9/31 (29%)
WD40 repeat 66..119 CDD:293791 10/53 (19%)
WD40 repeat 124..180 CDD:293791 10/55 (18%)
WD40 repeat 190..224 CDD:293791 8/34 (24%)
WD40 repeat 236..275 CDD:293791 13/38 (34%)
WD40 repeat 294..330 CDD:293791 8/35 (23%)
WD40 repeat 357..391 CDD:293791
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C157345733
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4155
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_103719
Panther 1 1.100 - - LDO PTHR44090
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1078
SonicParanoid 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
76.730

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