DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG3909 and RAD28

DIOPT Version :9

Sequence 1:NP_649969.1 Gene:CG3909 / 41226 FlyBaseID:FBgn0027524 Length:331 Species:Drosophila melanogaster
Sequence 2:NP_010313.3 Gene:RAD28 / 851594 SGDID:S000002437 Length:506 Species:Saccharomyces cerevisiae


Alignment Length:353 Identity:66/353 - (18%)
Similarity:122/353 - (34%) Gaps:100/353 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    21 WGRDTAASDPDDAVVEPEENPFDFDKKEARPKDFLVTGGLDDLVKVWD-------LQEDNTLKLR 78
            ||.|.:....|:...|......::.|::....|       |:..::..       :.::||::|.
Yeast    84 WGLDESLHRNDEGEQELINKRLNYIKRQPHQSD-------DEPAQIMGYKNKRTRINDNNTMRLV 141

  Fly    79 HKLKGHALGVVSVAVSSDGQTIASSSLDSTMCLWDARSGDKKHLLSFGPVDLWTVQFSPCNKYVI 143
            |..                ||              .|:..:.:..|...|        |..:..|
Yeast   142 HSF----------------QT--------------QRNKYRMYRQSSAAV--------PVQRSHI 168

  Fly   144 SGLNDGKISMYSVETGKAEQTLDAQNGKYTLSIA--YSPDGKYIASGAIDGIITIFDVAAGKVVQ 206
            |...|..|. :|....:.:......:.||.::..  |..|.....:|:.|..:.|:|....:.||
Yeast   169 SNKTDSPIG-FSETLSETDSEASISHHKYGITTLKWYKADNGMFFTGSNDKTVKIWDTNRFEAVQ 232

  Fly   207 TLE-GHAMPVRSLCFSPNSQLLLTASDDGHMKLYDV--THSDV----VGTLSGHASWVLCVAFSE 264
            .:. |:.:.........:|.||:.||:|.:.:|.|:  .:|.|    :|..:...|.:||..|:.
Yeast   233 DINLGYKINQIDNNVVDDSSLLVVASEDYYPRLIDLRTMNSGVTALGMGNQTRMQSEILCCKFNP 297

  Fly   265 DGKH-FASSSSDNSVKIWDTSERKCLHT------------------------FAEH--------- 295
            ..:. .|....:..||:||...|..|::                        |:.:         
Yeast   298 VREQIIACGDMEGGVKLWDLRMRNRLYSELKRNKNRFKTINNDDNDDQSDVYFSSNQSKAHLRCC 362

  Fly   296 TDQVWGVRYSPGNDKVASASEDKSLNIY 323
            :|.||.   |.|:: :.|...|..||::
Yeast   363 SDIVWN---SEGSE-LCSVGMDGKLNVW 386

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3909NP_649969.1 WD40 52..323 CDD:238121 60/320 (19%)
WD40 <54..326 CDD:225201 59/320 (18%)
WD40 repeat 89..127 CDD:293791 4/37 (11%)
WD40 repeat 130..166 CDD:293791 6/35 (17%)
WD40 repeat 174..209 CDD:293791 8/36 (22%)
WD40 repeat 215..251 CDD:293791 11/41 (27%)
WD40 repeat 257..293 CDD:293791 10/60 (17%)
WD40 repeat 299..323 CDD:293791 8/23 (35%)
RAD28NP_010313.3 WD40 1..386 CDD:225201 66/351 (19%)
WD40 repeat 61..102 CDD:293791 5/17 (29%)
WD40 repeat 108..170 CDD:293791 14/106 (13%)
WD40 repeat 198..233 CDD:293791 7/34 (21%)
WD40 repeat 241..279 CDD:293791 10/37 (27%)
WD40 repeat 290..351 CDD:293791 10/60 (17%)
WD40 repeat 362..388 CDD:293791 9/29 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4155
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.