DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3909 and Wdr53

DIOPT Version :9

Sequence 1:	NP_649969.1	Gene:	CG3909 / 41226	FlyBaseID:	FBgn0027524	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	XP_006248521.1	Gene:	Wdr53 / 498097	RGDID:	1559546	Length:	380	Species:	Rattus norvegicus

Alignment Length:	298	Identity:	72/298 - (24%)
Similarity:	110/298 - (36%)	Gaps:	88/298 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 VVEPEENPFDFDKKEARPKDFLVTGGLDD--LVKVWDLQEDNTLKLRHKLKGHALGVVSVAVSSD 96
            |.|.|.|....::.|:      :....||  .:|:.||::.   |:...||.|:....|||....
  Rat   114 VNEEEINCLSLNETES------LLASADDSGAIKILDLEKK---KVTRSLKRHSNICSSVAFRPQ 169

  Fly    97 -GQTIASSSLDSTMCLWDARSGDKKHLLSFGPVDLWTVQFSPCNKYVISGLNDGKISMYSVETGK 160
             .|::.|..||..:.||.        |....||  |                     :.:::..:
  Rat   170 RPQSLVSCGLDMQVMLWS--------LQKARPV--W---------------------ITNLQEDE 203

  Fly   161 AEQTLDAQ------NGKYTLSIAYSPDGKYIASGAIDGIITIFDVAAGKVVQTL--EGHAMPVRS 217
            .|:|...|      |.....||:.:..|...:.||.||.:.||.|...|..:.|  :||.:.|..
  Rat   204 TEETEGPQTPGRLLNPALAHSISVASCGNIFSCGAEDGKVRIFRVMGVKCERELGFKGHTLGVSQ 268

  Fly   218 LCFSPNSQLLLTASDDGHMKLYDVTHSDVVGTLSGHASWVLCVAFSEDGKHFASSSSDNSVKIWD 282
            :||.|.|.||||..:||.::|:||:                       ||  ......:.||
  Rat   269 VCFLPESHLLLTGGNDGKIRLWDVS-----------------------GK--MEKQQKSPVK--- 305

  Fly   283 TSERKCLHTFAEHTDQVWGVRYSPGNDKVASASEDKSL 320
                   |...:.|.:  .||.:...|..|..:||:.|
  Rat   306 -------HIHRKKTKR--AVRPTQSGDSRAPGAEDEGL 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3909	NP_649969.1	WD40	52..323	CDD:238121	67/280 (24%)
		WD40	<54..326	CDD:225201	67/278 (24%)
		WD40 repeat	89..127	CDD:293791	10/38 (26%)
		WD40 repeat	130..166	CDD:293791	3/35 (9%)
		WD40 repeat	174..209	CDD:293791	12/36 (33%)
		WD40 repeat	215..251	CDD:293791	14/35 (40%)
		WD40 repeat	257..293	CDD:293791	5/35 (14%)
		WD40 repeat	299..323	CDD:293791	7/22 (32%)
Wdr53	XP_006248521.1	WD40	<30..303	CDD:225201	61/253 (24%)
		WD40	30..291	CDD:295369	57/216 (26%)
		WD40 repeat	35..71	CDD:293791
		WD40 repeat	77..114	CDD:293791	72/298 (24%)
		WD40 repeat	119..155	CDD:293791	8/44 (18%)
		WD40 repeat	162..208	CDD:293791	14/76 (18%)
		WD40 repeat	222..260	CDD:293791	12/37 (32%)
		WD40	259..>380	CDD:225201	29/113 (26%)
		WD40 repeat	266..292	CDD:293791	12/25 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000