DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3909 and SPCC126.01c

DIOPT Version :9

Sequence 1:	NP_649969.1	Gene:	CG3909 / 41226	FlyBaseID:	FBgn0027524	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_588444.2	Gene:	SPCC126.01c / 2538691	PomBaseID:	SPCC126.01c	Length:	369	Species:	Schizosaccharomyces pombe

Alignment Length:	341	Identity:	67/341 - (19%)
Similarity:	127/341 - (37%)	Gaps:	95/341 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KEENAHDSQLWACTWGRDTAASDPDDAVVEPEENP---------FDFDKKEARPKDF--LVTGGL 60
            |||.:|:                       |..||         .:.|:...:.|.|  |.....
pombe    22 KEEKSHN-----------------------PNGNPRNLKAKILNIELDRTTPKKKQFPRLFVCEA 63

  Fly    61 DDLVKVWDLQEDNTLKLRHKLKGHALGVVSVAVSS---DGQTIASSSLDSTMCLWDARSGDKKHL 122
            ..:.|::||:.:.|.|   ..|||:..|....:.|   ||:.
pombe    64 SHICKLYDLEINKTCK---TYKGHSGPVTCCQIESLRKDGKV----------------------- 102

  Fly   123 LSFGPVDLWTVQFSPCNKYVISGLNDGKISMYSVETGKAEQTLDAQNGKYTLSIAYSPDGKYIAS 187
                             :::.:|..|..|..::|.||:..:||..........:....:| .:.|
pombe   103 -----------------RHIYTGSWDHTIKKWNVSTGECVETLIGHTDYVKCLLLLEEEG-LLLS 149

  Fly   188 GAIDGIITIFDVAA--GKVVQTLEGHAMPVRSLCFSPNSQLLLTASDDGHMKLYDVTHSDVVGT- 249
            |:.|..:.::||::  .:::..|.||:..:..:...||:.:..|...:..::.:.:|  .|.|:
pombe   150 GSTDASLIVWDVSSQPSRLLYKLTGHSRGIECITRQPNTDIFWTCGSESSIRCWHIT--KVGGSQ 212

  Fly   250 -----LSGHASWVLCVAFS-EDGKHFASSSSDNSVKIWDTSERKCLHTFAEHTDQVWGV-RYSPG 307
                 ..||.|.|.|:.|. :|.:...::|:|.:|:.|...:.....|..||.|....| ..:.|
pombe   213 LEEEGFWGHQSNVYCLLFDPQDSEALWTASADKTVREWSLYQGIHEETRMEHPDVCTDVLTLADG 277

  Fly   308 NDKVASASEDKSLNIY 323
            |  :|:|..|:.:.::
pombe   278 N--IATACRDEEIRVW 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3909	NP_649969.1	WD40	52..323	CDD:238121	59/285 (21%)
		WD40	<54..326	CDD:225201	58/285 (20%)
		WD40 repeat	89..127	CDD:293791	3/40 (8%)
		WD40 repeat	130..166	CDD:293791	7/35 (20%)
		WD40 repeat	174..209	CDD:293791	6/36 (17%)
		WD40 repeat	215..251	CDD:293791	6/41 (15%)
		WD40 repeat	257..293	CDD:293791	9/36 (25%)
		WD40 repeat	299..323	CDD:293791	6/24 (25%)
SPCC126.01c	NP_588444.2	WD40	54..332	CDD:238121	58/286 (20%)
		WD40	<58..334	CDD:225201	57/282 (20%)
		WD40 repeat	89..130	CDD:293791	11/80 (14%)
		WD40 repeat	135..173	CDD:293791	6/38 (16%)
		WD40 repeat	180..217	CDD:293791	6/38 (16%)
		WD40 repeat	225..263	CDD:293791	9/37 (24%)
		WD40 repeat	271..307	CDD:293791	6/23 (26%)
		WD40 repeat	309..331	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	1	0.960