DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3909 and F02E9.10

DIOPT Version :9

Sequence 1:	NP_649969.1	Gene:	CG3909 / 41226	FlyBaseID:	FBgn0027524	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_001122441.1	Gene:	F02E9.10 / 172630	WormBaseID:	WBGene00008533	Length:	455	Species:	Caenorhabditis elegans

Alignment Length:	281	Identity:	71/281 - (25%)
Similarity:	120/281 - (42%)	Gaps:	16/281 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 DLVKVWDLQED--NTLKL--RHKLKGHALGVVSVAVSSDGQTIASSSLDSTMCLWDARSGDKKHL 122
            |..|:|.||||  |.:.|  |..|......:.:..:|.||:.:.:..::|.:...:..:..|...
Worm    47 DCSKLWILQEDSSNNISLDERMVLAKWRTAIQAADISVDGKYMVAVGMNSIVYEVELVNTVKSMA 111

  Fly   123 LSFGPVDLWTVQFSPCNKYVISGLNDGKISMYSVETGKAEQTLDAQNGKYTLSIAYSPDGKYIAS 187
            ..||.:|......||.....::....|.::.....:.:..:.......|....:.||.|.||:|.
Worm   112 FDFGYLDAVFCAVSPLKTGYVTASYSGHLNEIQHSSNEIIRQEPFPTVKQISCLKYSRDAKYLAI 176

  Fly   188 GAIDGIITIFDVAAGKVVQTLEGHAMPVRSLCFSPNSQLLLTASDDGHMKLY---DVTHSD---- 245
            |.:||.|.:......|.....|.|:|.:|.:.|.||.:..|:|.||..:||:   :.|.:|
Worm   177 GQLDGAIEMLYSENFKNYHKYEVHSMRIRKIEFLPNEERFLSACDDRLIKLHSLSEFTETDPSRS 241

  Fly   246 --VVGTLSGHASWVLCVAFSE--DGKHFASSSSDNSVKIWDTSERKCLHTFA-EHTDQVWGVRYS 305
              .:...|.|.:.|..:...|  .|..|||||:.:.:.||.......:.:.. |||..:..:.:|
Worm   242 TKAIRVYSAHDAPVTGLTIDEKSGGTRFASSSASSQIFIWHIEMTTPIMSITNEHTSTISALSFS 306

  Fly   306 PGNDKVASASEDKSLNIYYCP 326
            |.:..:.|..:|..:.||..|
Worm   307 PTSRHLLSGGDDAMILIYRIP 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3909	NP_649969.1	WD40	52..323	CDD:238121	68/276 (25%)
		WD40	<54..326	CDD:225201	70/279 (25%)
		WD40 repeat	89..127	CDD:293791	6/37 (16%)
		WD40 repeat	130..166	CDD:293791	3/35 (9%)
		WD40 repeat	174..209	CDD:293791	11/34 (32%)
		WD40 repeat	215..251	CDD:293791	12/44 (27%)
		WD40 repeat	257..293	CDD:293791	10/37 (27%)
		WD40 repeat	299..323	CDD:293791	4/23 (17%)
F02E9.10	NP_001122441.1	WD40	41..325	CDD:392136	69/277 (25%)
		WD40 repeat	77..113	CDD:293791	5/35 (14%)
		WD40 repeat	121..155	CDD:293791	3/33 (9%)
		WD40 repeat	162..199	CDD:293791	11/36 (31%)
		WD40 repeat	205..250	CDD:293791	12/44 (27%)
		WD40 repeat	255..293	CDD:293791	10/37 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR44090
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010