DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mical and PLIM2c

DIOPT Version :9

Sequence 1:	NP_001247015.1	Gene:	Mical / 41225	FlyBaseID:	FBgn0053208	Length:	4743	Species:	Drosophila melanogaster
Sequence 2:	NP_191682.2	Gene:	PLIM2c / 825295	AraportID:	AT3G61230	Length:	213	Species:	Arabidopsis thaliana

Alignment Length:	186	Identity:	48/186 - (25%)
Similarity:	74/186 - (39%)	Gaps:	49/186 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly  1055 EANSDEKNAGSSNATTNTNNTVIPKSSSKVALAFKKQAASEKCRFCKQTVYLMEKTTVEGLVLHR 1119
            |:.:..||..::..|..:|:..  |:.::::..|  ....:||..||:|||.:||.|:||...|:
plant    69 ESGNFSKNFQTAGKTEKSNDAT--KAPNRLSSFF--SGTQDKCAACKKTVYPLEKMTMEGESYHK 129

  Fly  1120 NCLKCHHCHTNLRLGGY-AFDRDDPQGRFYCTQHFRLPPKPLPQ------RTNKARKSAAAQPAS 1177
            .|.:|.|....|....| |.|     |..||..||       .|      ..|...::||....|
plant   130 TCFRCAHSGCPLTHSSYAALD-----GVLYCKVHF-------SQLFLEKGNYNHVLQAAANHRRS 182

  Fly  1178 PAVPPTAGSVPTAAATSEHMDTTPPRDQVDLLETSRANASADAMSDDEANVIDEHE 1233
                           |:|...|.|..|:.:..|...::|:|           :|||
plant   183 ---------------TAEEDKTEPKEDEANPTEEETSDAAA-----------EEHE 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mical	NP_001247015.1	MDR	<114..>160	CDD:302572
		CH	563..>629	CDD:294029
		LIM_Mical	1097..1153	CDD:188823	22/56 (39%)
		Ehrlichia_rpt	<2081..2479	CDD:118064
		DUF3585	4592..4705	CDD:288945
PLIM2c	NP_191682.2	LIM1_SF3	7..69	CDD:188824	48/186 (26%)
PLIM2c	NP_191682.2	LIM	107..167	CDD:413332	25/71 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	56	1.000	Domainoid score	I4039
eggNOG	1	0.900	-	-		E2759_KOG1700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2983
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810