DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mical and Crip2

DIOPT Version :9

Sequence 1:	NP_001247015.1	Gene:	Mical / 41225	FlyBaseID:	FBgn0053208	Length:	4743	Species:	Drosophila melanogaster
Sequence 2:	NP_077185.1	Gene:	Crip2 / 68337	MGIID:	1915587	Length:	208	Species:	Mus musculus

Alignment Length:	119	Identity:	35/119 - (29%)
Similarity:	51/119 - (42%)	Gaps:	21/119 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly  1094 SEKCRFCKQTVYLMEKTTVEGLVLHRNCLKCHHCHTNLRLGGYAFDRDDPQGRFYCTQHFRLPPK 1158
            :.||..|.:|||..||.:..|...|:.||||..|:..|..||:|    :..|:.:|  |     |
Mouse     2 ASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCNKTLTPGGHA----EHDGKPFC--H-----K 55

  Fly  1159 PL------PQRTN--KARKSAAAQPASPAVPPTAGSVPTAAATSEHMDTT-PPR 1203
            |.      |:..|  .|......:|.:.| |...|.:......:|...|: ||:
Mouse    56 PCYATLFGPKGVNIGGAGSYIYEKPQTEA-PQVTGPIEVPVVRTEERKTSGPPK 108

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mical	NP_001247015.1	MDR	<114..>160	CDD:302572
		CH	563..>629	CDD:294029
		LIM_Mical	1097..1153	CDD:188823	20/55 (36%)
		Ehrlichia_rpt	<2081..2479	CDD:118064
		DUF3585	4592..4705	CDD:288945
Crip2	NP_077185.1	LIM1_TLP	5..58	CDD:188860	23/63 (37%)
Crip2	NP_077185.1	LIM1_TLP	126..179	CDD:188860
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900