DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mical and ZK622.5

DIOPT Version :9

Sequence 1:	NP_001247015.1	Gene:	Mical / 41225	FlyBaseID:	FBgn0053208	Length:	4743	Species:	Drosophila melanogaster
Sequence 2:	NP_001040831.1	Gene:	ZK622.5 / 4363029	WormBaseID:	WBGene00044667	Length:	182	Species:	Caenorhabditis elegans

Alignment Length:	169	Identity:	40/169 - (23%)
Similarity:	63/169 - (37%)	Gaps:	57/169 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly  2172 CDKSSNSSRRGSQSSLIMSRRHSEISLNEKLNQDALAALNQI--EKEREAEQVDELFQSMVEEME 2234
            ||.|:..             .|..::||  |..||...|..|  ...:||.::::...:.:.|:.
Worm    44 CDDSAKG-------------HHINVTLN--LRNDAGDTLETIHFRNSKEAIEIEDHAANNITEVV 93

  Fly  2235 QEPQPTAIVEPPEEDIDADSLCTTISKSPSAQPVTVVKRGSSEDQSIEKLFSHFSDEMLVNVEFD 2299
            .    ||.|.|...:|               |.|:|..|        :.||     ::.||.|.|
Worm    94 L----TADVAPVPYNI---------------QKVSVRIR--------DNLF-----KLHVNQECD 126

  Fly  2300 SNDELVGITPRATLVSR--NTEDRD-YLDKLESLERDEE 2335
            ..|:.:..|.:.|..||  :.|.:| |.|     :|.:|
Worm   127 DEDDFITSTTQQTFWSRRIDCERKDVYCD-----DRHDE 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mical	NP_001247015.1	MDR	<114..>160	CDD:302572
		CH	563..>629	CDD:294029
		LIM_Mical	1097..1153	CDD:188823
		Ehrlichia_rpt	<2081..2479	CDD:118064	40/169 (24%)
		DUF3585	4592..4705	CDD:288945
ZK622.5	NP_001040831.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900