Protein Alignment Mical and Mlp84B

DIOPT Version :10

• Sequence 1: NP_001247015.1
• Gene: Mical / 41225
• FlyBaseID: FBgn0053208
• Length: 4743
• Species: Drosophila melanogaster
• Sequence 2: NP_477122.1
• Gene: Mlp84B / 40849
• FlyBaseID: FBgn0014863
• Length: 495
• Species: Drosophila melanogaster
• Alignment Length: 425
• Identity: 91/425 - (21%)
• Similarity: 139/425 - (32%)
• Gaps: 120/425 - (28%)

  Fly   903 RERGDIPS----------ALPRTADEQFSDRIKN---MEQRMTGRG--------GLGGDKKPKDL 946
            ||.||:||          |:.|..:.:...|...   ..::|..||        ..|..||..|.
  Fly    92 RENGDVPSVRNGARLEPRAIARAPEGEGCPRCGGYVYAAEQMLARGRSWHKECFKCGTCKKGLDS 156

  Fly   947 MRAIGKIDSN--------------------------------DWNVREIEKKIELSKKTEIHGPK 979
            :......|.|                                |....:|...|::.|   |....
  Fly   157 ILCCEAPDKNIYCKGCYAKKFGPKGYGYGQGGGALQSDCYAHDDGAPQIRAAIDVDK---IQARP 218

  Fly   980 GREKVPKWSKEQFQARQHKMSKPQRQDSREAEKFKDIDQTIRNLDKQLKEGHNLDV------GER 1038
            | |..|:.....:.|.| |:|| .|:..::....||..:|:.:::  ..:|.:.||      |::
  Fly   219 G-EGCPRCGGVVYAAEQ-KLSK-GREWHKKCFNCKDCHKTLDSIN--ASDGPDRDVYCRTCYGKK 278

  Fly  1039 -GRNKVASIAGQ-FGKKDEANSDEKNAGSSNATTNTNNTVIPKSSSKVALAFKKQAASEKCRFCK 1101
             |.:......|. |.:.|....|:.:|  :....|.:.|.|            |....|.|..|.
  Fly   279 WGPHGYGFACGSGFLQTDGLTEDQISA--NRPFYNPDTTSI------------KARDGEGCPRCG 329

  Fly  1102 QTVYLMEKTTVEGLVLHRNCLKCHHCHTNLRLGGYAFDRDDPQGRFYCTQHF--RLPPKPL---- 1160
            ..|:..|:...:|.|.|:.|..|..||..|   ......|.|.|..:|...:  ...||..
  Fly   330 GAVFAAEQQLSKGKVWHKKCYNCADCHRPL---DSVLACDGPDGDIHCRACYGKLFGPKGFGYGH 391

  Fly  1161 -PQRTNKARKSAAAQP-ASP-AVPPTAGSVPT---AAATSEHMDTTPPRDQVDLLETSRANASAD 1219
             |...:.:.:|....| ..| |.|.|:|..|.   |...:|.|          :.:|...:....
  Fly   392 APTLVSTSGESTIQFPDGRPLAGPKTSGGCPRCGFAVFAAEQM----------ISKTRIWHKRCF 446

  Fly  1220 AMSD-----DEANVIDEHEWS-------GRNFLPE 1242
            ..||     |..|:.|..:..       ||||.|:
  Fly   447 YCSDCRKSLDSTNLNDGPDGDIYCRACYGRNFGPK 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mical	NP_001247015.1	UbiH	128..>263	CDD:440419
		CH_SF	567..669	CDD:469584
		LIM_Mical	1097..1153	CDD:188823	16/55 (29%)
		PRK10819	<1450..>1557	CDD:236768
		bMERB_dom	4592..4705	CDD:463467
Mlp84B	NP_477122.1	LIM1_MLP84B_like	11..64	CDD:188788
		LIM_CRP_like	120..173	CDD:188712	10/52 (19%)
		LIM_CRP_like	222..275	CDD:188712	13/56 (23%)
		LIM_CRP_like	325..378	CDD:188712	16/55 (29%)
		LIM_CRP_like	421..474	CDD:188712	10/62 (16%)