DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mical and Csrp1

DIOPT Version :9

Sequence 1:	NP_001247015.1	Gene:	Mical / 41225	FlyBaseID:	FBgn0053208	Length:	4743	Species:	Drosophila melanogaster
Sequence 2:	NP_058844.1	Gene:	Csrp1 / 29276	RGDID:	62053	Length:	193	Species:	Rattus norvegicus

Alignment Length:	120	Identity:	36/120 - (30%)
Similarity:	45/120 - (37%)	Gaps:	24/120 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  1030 GHNLDVGERGRNKVASIAGQFGKKDEANSDEKNAGSSNATTNTNNTVIPKSSSKVALAFKKQAAS 1094
            |:....|....:|..|:    |.|.|      .|.....|||.|       :||.|   :|...|
  Rat    72 GYGQGAGTLSMDKGESL----GIKHE------EAPGHRPTTNPN-------ASKFA---QKIGGS 116

  Fly  1095 EKCRFCKQTVYLMEKTTVEGLVLHRNCLKCHHCHTNLRLGGYAFDRDDPQGRFYC 1149
            |:|..|.|.||..||....|...|::|.:|..|...|.....|    |..|..||
  Rat   117 ERCPRCSQAVYAAEKVIGAGKSWHKSCFRCAKCGKGLESTTLA----DKDGEIYC 167

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mical	NP_001247015.1	MDR	<114..>160	CDD:302572
		CH	563..>629	CDD:294029
		LIM_Mical	1097..1153	CDD:188823	18/53 (34%)
		Ehrlichia_rpt	<2081..2479	CDD:118064
		DUF3585	4592..4705	CDD:288945
Csrp1	NP_058844.1	LIM1_CRP1	8..63	CDD:188863
		Nuclear localization signal. /evidence=ECO:0000255	64..69
		LIM2_CRP	119..172	CDD:188787	18/53 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810