Protein Alignment Spn85F and SERPINB5

DIOPT Version :10

• Sequence 1: NP_649965.2
• Gene: Spn85F / 41221
• FlyBaseID: FBgn0037772
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_002630.2
• Gene: SERPINB5 / 5268
• HGNCID: 8949
• Length: 375
• Species: Homo sapiens
• Alignment Length: 302
• Identity: 57/302 - (18%)
• Similarity: 106/302 - (35%)
• Gaps: 72/302 - (23%)

  Fly   386 YKDLDANLFLTLFNPHTHVPH----HPLHFPPPVPAAFAPITNDF----EPHYIGEAAEGKSNYN 442
            |.|...|| .|.|...|..|:    ..:.|...:......|.|..    :.|:....|:...|..
Human    93 YVDKSLNL-STEFISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQ 156

  Fly   443 TD--VISHVFYLG-------NQQVVHTTFKV------------YNAVLYYKYFEHLKMSVLELEL 486
            |.  |::..:::|       ..:.....|:|            ..|.......:.:...::||..
Human   157 TKILVVNAAYFVGKWMKKFSESETKECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPF 221

  Fly   487 DTPEYNLMILLPDYHTDIVAAAASLKLGPTLRLMRKQLK----PRW----------VQAIIPDFK 537
            .....::.||||   .|:...:..|:      .:.|||.    .:|          |:..||.||
Human   222 QNKHLSMFILLP---KDVEDESTGLE------KIEKQLNSESLSQWTNPSTMANAKVKLSIPKFK 277

  Fly   538 LHGTMFLTNDLQNMGICDVFEPNRADFRPMTEEKGVYVRHIEQSIDVTIRTHPINQLKRNYGAQS 602
            :...:.....|:|:|:..:|..:.:||..|:|.|||.:.::...:.:.|...         |..|
Human   278 VEKMIDPKACLENLGLKHIFSEDTSDFSGMSETKGVALSNVIHKVCLEITED---------GGDS 333

  Fly   603 KPI----------QISVNHPFLFFIVDRDLDVAVMSGRILNP 634
            ..:          :::.:|||::.|........:..|:..:|
Human   334 IEVPGARILQHKDELNADHPFIYIIRHNKTRNIIFFGKFCSP 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn85F	NP_649965.2	serpin	72..>174	CDD:476815
		Serpin	<450..634	CDD:459662	40/226 (18%)
SERPINB5	NP_002630.2	serpinB5_maspin	1..375	CDD:381013	56/300 (19%)