Protein Alignment Spn85F and agt

DIOPT Version :10

• Sequence 1: NP_649965.2
• Gene: Spn85F / 41221
• FlyBaseID: FBgn0037772
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_932329.1
• Gene: agt / 322485
• ZFINID: ZDB-GENE-030131-1205
• Length: 454
• Species: Danio rerio
• Alignment Length: 631
• Identity: 119/631 - (18%)
• Similarity: 192/631 - (30%)
• Gaps: 238/631 - (37%)

  Fly    25 IDHEEFRASGFPHPHFPPPPLTPLDHLPQVLAA----KELTP-AEVMVDLTNDLTHRLLHYHSIL 84
            |..||.:.....||..|.|..|..|  |:..:|    |.||. ..|:.:|.|.|..|:   :..|
Zfish    39 IQSEEHKPLETVHPLPPLPGSTDPD--PRTASAAESLKNLTQRTAVLAELQNSLGLRM---YQTL 98

  Fly    85 NR----NNFAFSPTALVSVLVALFEGSAGNTAEELRHVLQLPNNRDVTRVGY-RDIHRRLRTYFF 144
            :|    .|...||......||.|:.|::..||...:.:|.|....:.|...| .|.|..|||
Zfish    99 SRTQKHTNTLLSPLNAFGALVTLYLGASKKTAISYQQLLGLNLESEQTDCAYFVDGHTVLRT--- 160

  Fly   145 GSDNPLKGLSLNKGNVTVLKDFETVLMFY---GYDLSVDMLSSTPANLTSDAELVNTTMASNTTT 206
                 |:.:|.:.....  |:..|::..:   ..|||.:.|..|..  .||...|.:
Zfish   161 -----LQAISAHVDESR--KELRTLVWTFVNSDADLSKEFLRGTQD--FSDDSFVRS-------- 208

  Fly   207 MEMDAETTTSKDAESTTEEPATTTTEPPATTTAEPPTTTTETPAETEATTEAPAATSGEEEAAEP 271
                .:.:.:||||..
Zfish   209 ----VDFSQAKDAEVE------------------------------------------------- 220

  Fly   272 AGEDEAAELVSAFVAEEDSEPLLRIQKARVSRLPTSKLQAPLKHSNPITPKPIYLPSARTVAMPM 336
                     |:.|           |||.     ..:|:::..|   .:|||...|
Zfish   221 ---------VNNF-----------IQKT-----SDNKVKSMFK---GVTPKTDLL---------- 247

  Fly   337 PMMARQVAERKPPGTRQVISIIAPSVQPANISVTRKTKTARYKRHAIPAYKDLDANLFLTLFNPH 401
                                 .|.||
Zfish   248 ---------------------FASSV--------------------------------------- 252

  Fly   402 THVPHHPLHFPPPVPAAFAPITNDFEPHYIGEAAEGKSNYNTDVISHVFYLGNQQVVHTTFKVYN 466
                    ||......||.|              |..|:.:       |:......|...|.::.
Zfish   253 --------HFKGNWKTAFQP--------------EATSDQD-------FWTQKNSSVQVPFMMHT 288

  Fly   467 AVLYYKYFEHL--KMSVLELELDTPEYNLMIL------LPDYHTDIVAAAASLKLGPTLRLMRKQ 523
            .  .|||.:..  |.|::.|.|....:.|::|      |.|....:      |.:.||   ..:.
Zfish   289 G--DYKYLDDAGRKCSIVRLGLSKRTFMLLVLPHEGASLQDIEKPL------LTVIPT---WLRH 342

  Fly   524 LKPRWVQAIIPDFKLHGTMFLTNDLQNMGICDVFEPNRADFRPMTEEKGVYVRHIEQSIDVTIRT 588
            ||.::::..:|.|.|.....|.:.|..|.:......:.|.||.|:.::...|..:...: |...|
Zfish   343 LKEKYLELSLPKFSLTAVTDLRSVLSEMAVEKYLMGSDASFRRMSSKENFTVDKVLNKV-VFEMT 406

  Fly   589 HPINQLKRNYGAQSKPIQISVNHPFLFFIVDRDLDVAVMSGRILNP 634
            ...::::........|.:::.|.||.|.:|:.:.:..:|.|:|:||
Zfish   407 EGGSEVQNRTDDGRAPHKVTFNRPFFFAVVEGNSNAILMLGKIINP 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn85F	NP_649965.2	serpin	72..>174	CDD:476815	26/109 (24%)
		Serpin	<450..634	CDD:459662	41/191 (21%)
agt	NP_932329.1	serpinA8_AGT	22..454	CDD:381010	119/631 (19%)