Protein Alignment Spn85F and Serpinb5

DIOPT Version :10

• Sequence 1: NP_649965.2
• Gene: Spn85F / 41221
• FlyBaseID: FBgn0037772
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_033283.1
• Gene: Serpinb5 / 20724
• MGIID: 109579
• Length: 375
• Species: Mus musculus
• Alignment Length: 606
• Identity: 95/606 - (15%)
• Similarity: 167/606 - (27%)
• Gaps: 261/606 - (43%)

  Fly    57 AKELTPAEVMVDLTNDLTHRLLHYHSILNRNNFAFSPTALVSVLVALFEGSAGNTAEELRHVLQL 121
            |..|..:...|||...|..|       ....|..|||..|.:.|.....|:.|:||.|:..||..
Mouse     3 ALRLANSAFAVDLFKQLCER-------DPAGNILFSPICLSTSLSLAQVGTKGDTANEIGQVLHF 60

  Fly   122 PNNRDVTRVGYRDIHRRLRTYFFGSDNPLKGLSLNKGNVTVLKDFETVLMFYGYDLSVDMLSSTP 186
            .|.:||.               ||..             ||..|...:..||...|
Mouse    61 ENVKDVP---------------FGFQ-------------TVTSDVNKLSSFYSLKL--------- 88

  Fly   187 ANLTSDAELVNTTMASNTTTMEMDAETTTSKDAESTTEEPATTTTEPPATTTAEPPTTTTETPAE 251
                             ...:.:|.....|.:..|:|:.|.....|     |.:......||..:
Mouse    89 -----------------VKRLYIDKSLNPSTEFISSTKRPYAKELE-----TVDFKDKLEETKGQ 131

  Fly   252 TEATTEAPAATSGEEEAAEPAGEDEAAELV---SAFVAEEDSEPLLRIQKARVSRLPTSKL-QAP 312
            ..::.:.......|:..:|.:..|:...||   :.||.:            .:.:.|.|:. :.|
Mouse   132 INSSIKELTDGHFEDILSENSISDQTKILVVNAAYFVGK------------WMKKFPESETKECP 184

  Fly   313 LKHSNPITPKPIYLPSARTVAMPMPMMARQVAERKPPGTRQVISIIAPSVQPANISVTRKTKTAR 377
            .:.|             :|...|:.||                          |:..|
Mouse   185 FRIS-------------KTDTKPVQMM--------------------------NLEAT------- 203

  Fly   378 YKRHAIPAYKDLDANLFLTLFNPHTHVPHHPLHFPPPVPAAFAPITNDFEPHYIGEAAEGKSNYN 442
                                                                             
Mouse   204 ----------------------------------------------------------------- 203

  Fly   443 TDVISHVFYLGNQQVVHTTFKVYNAVLYYKYFEHLKMSVLELELDTPEYNLMILLPDYHTDIVAA 507
                   |.|||                   .:.:...::||.......:::|:||   .|:...
Mouse   204 -------FCLGN-------------------IDDISCKIIELPFQNKHLSMLIVLP---KDVEDE 239

  Fly   508 AASLKLGPTLRLMRKQLKP----RW----------VQAIIPDFKLHGTMFLTNDLQNMGICDVFE 558
            :..|:      .:.:||.|    :|          |:..:|.||:...:.....|:::|:..:|.
Mouse   240 STGLE------KIEQQLNPETLLQWTNPSTMANAKVKLSLPKFKVEKMIDPKASLESLGLKSLFN 298

  Fly   559 PNRADFRPMTEEKGVYVRHIEQSIDVTIRTHPINQLKRNYGAQSKPI----------QISVNHPF 613
            .:.:||..|:|.|||.:.::...:.:.|...         |.:|..:          :.:.:|||
Mouse   299 ESTSDFSGMSETKGVSLSNVIHRVCLEITED---------GGESIEVPGSRILQHKDEFNADHPF 354

  Fly   614 LFFIVDRDLDVAVMSGRILNP 634
            ::.|........:..|:..:|
Mouse   355 IYIIRHNKTRNIIFFGKFCSP 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn85F	NP_649965.2	serpin	72..>174	CDD:476815	24/101 (24%)
		Serpin	<450..634	CDD:459662	37/207 (18%)
Serpinb5	NP_033283.1	serpinB5_maspin	1..375	CDD:381013	94/604 (16%)