Protein Alignment Spn85F and Serpinb5

DIOPT Version :10

• Sequence 1: NP_649965.2
• Gene: Spn85F / 41221
• FlyBaseID: FBgn0037772
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_476449.2
• Gene: Serpinb5 / 116589
• RGDID: 69342
• Length: 375
• Species: Rattus norvegicus
• Alignment Length: 582
• Identity: 92/582 - (15%)
• Similarity: 150/582 - (25%)
• Gaps: 268/582 - (46%)

  Fly    88 NFAFSPTALVSVLVALFEGSAGNTAEELRHVLQLPNNRDVTRVGYRDIHRRLRTYFFGSDNPLKG 152
            |..|||..|.:.|.....|:.|:||.|:..||...|.:||.               ||..
  Rat    27 NILFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKDVP---------------FGFQ----- 71

  Fly   153 LSLNKGNVTVLKDFETVLMFYGYDLSVDMLSSTPANLTSDAELVNTTMASNTTTMEMDAETTTSK 217
                    |:..|...:..||...|...:......||::  |.:::|......    :.||...|
  Rat    72 --------TITSDVNKLSSFYSLKLIKRLYIDKSLNLST--EFISSTKRPYAN----ELETVDFK 122

  Fly   218 DAESTTEEPATTTTEPPATTTAEPPTTTTETPAETEATTEAPAATSGEEEAAEPAGEDEAAELV- 281
            |                         ...||..:..::.:.......|:...|.:..|:...||
  Rat   123 D-------------------------KLEETKGQINSSIKELTDGHFEDILPENSISDQTKILVV 162

  Fly   282 ----------SAFVAEEDSEPLLRIQKARVSRLPTSKLQAPLKHSNPITPKPIYLPSARTVAMPM 336
                      ..|...|..|...||.|
  Rat   163 NAAYFVGKWMKKFPESETKECPFRINK-------------------------------------- 189

  Fly   337 PMMARQVAERKPPGTRQVISIIAPSVQPANISVTRKTKTARYKRHAIPAYKDLDANLFLTLFNPH 401
                   .:.||             ||..|:..|
  Rat   190 -------TDTKP-------------VQMMNLEAT------------------------------- 203

  Fly   402 THVPHHPLHFPPPVPAAFAPITNDFEPHYIGEAAEGKSNYNTDVISHVFYLGNQQVVHTTFKVYN 466
                                                            |.|||
  Rat   204 ------------------------------------------------FCLGN------------ 208

  Fly   467 AVLYYKYFEHLKMSVLELELDTPEYNLMILLPDYHTDIVAAAASLKLGPTLRLMRKQLKP----R 527
                   .:.:...::||.......:::|:||   .|:...:..|:      .:.|||.|    :
  Rat   209 -------IDDINCKIIELPFQNKHLSMLIVLP---KDVEDESTGLE------KIEKQLNPETLLQ 257

  Fly   528 W----------VQAIIPDFKLHGTMFLTNDLQNMGICDVFEPNRADFRPMTEEKGVYVRHIEQSI 582
            |          |:..:|.||:...:.....|:::|:..:|..:.:||..|:|.|||.|.::...:
  Rat   258 WTNPSTMANAKVKLSLPKFKVEKMIDPKASLESLGLKSLFNESTSDFSGMSETKGVSVSNVIHRV 322

  Fly   583 DVTIRTHPINQLKRNYGAQSKPI----------QISVNHPFLFFIVDRDLDVAVMSGRILNP 634
            .:.|...         |..|..:          :...:|||||.:........|..|:..:|
  Rat   323 CLEITED---------GGDSIEVPGSRILQHKDEFKADHPFLFIVRHNKTRNIVFLGKFSSP 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn85F	NP_649965.2	serpin	72..>174	CDD:476815	21/85 (25%)
		Serpin	<450..634	CDD:459662	41/207 (20%)
Serpinb5	NP_476449.2	serpinB5_maspin	1..375	CDD:381013	91/580 (16%)