Protein Alignment Art4 and HMT1

DIOPT Version :10

• Sequence 1: NP_649963.1
• Gene: Art4 / 41219
• FlyBaseID: FBgn0037770
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_009590.1
• Gene: HMT1 / 852322
• SGDID: S000000238
• Length: 348
• Species: Saccharomyces cerevisiae
• Alignment Length: 358
• Identity: 119/358 - (33%)
• Similarity: 184/358 - (51%)
• Gaps: 49/358 - (13%)

  Fly   129 KSVFSQRTEESSASQ-YFQFYGYLSQQQNMMQDYVRTSTYQRAILGNAVDFQDKIVLDVGAGSGI 192
            |...:::|:.|.:.| ||..|.:....:.|:||.|||.:|:.||:.|...|:||||||||.|:||
Yeast     7 KDSATEKTKLSESEQHYFNSYDHYGIHEEMLQDTVRTLSYRNAIIQNKDLFKDKIVLDVGCGTGI 71

  Fly   193 LSFFAVQAGAAKVYAIEASNMAQYAQQLVESNNVQHKISVIPGKIEEIELP-EKVDVIISEPMGY 256
            ||.||.:.||..|..::.|::.:.|::|||.|....||:::.||:|::.|| .|||:||||.|||
Yeast    72 LSMFAAKHGAKHVIGVDMSSIIEMAKELVELNGFSDKITLLRGKLEDVHLPFPKVDIIISEWMGY 136

  Fly   257 MLYNERMLETYLHAR-KWLKPQGKMYPTHGDLHIAPFSDESLYSEQYNKANFWYQSAFHGVDLT- 319
            .|..|.|::|.|:|| .:|...|.::|....:|:|...| |.|.::  |.|:|..  .:|.|.:
Yeast   137 FLLYESMMDTVLYARDHYLVEGGLIFPDKCSIHLAGLED-SQYKDE--KLNYWQD--VYGFDYSP 196

  Fly   320 ----TLHKEGMKEYFRQPIVDTFDIRICMAKSVRHVCDFLNDK--EDDLHLISIP-------LEF 371
                .||         :|||||.:         |:..:..:||  |.||:.:.|.       .:.
Yeast   197 FVPLVLH---------EPIVDTVE---------RNNVNTTSDKLIEFDLNTVKISDLAFKSNFKL 243

  Fly   372 HILQTGICHGLAFWFDVEFSG--SSQNVWLSTSPTAPLTHWYQVRCLLPMPIFIKQGQTLTGRVL 434
            ...:..:.:|:..|||:.|..  ..:.|..||.|.||.|||.|.....|..:..:.|.|:.|.::
Yeast   244 TAKRQDMINGIVTWFDIVFPAPKGKRPVEFSTGPHAPYTHWKQTIFYFPDDLDAETGDTIEGELV 308

  Fly   435 LEANRRQSYDVTIDLH-------IEGTLISSSN 460
            ...|.:.:.|:.|.:.       |:|...|..|
Yeast   309 CSPNEKNNRDLNIKISYKFESNGIDGNSRSRKN 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Art4	NP_649963.1	PH-like	24..134	CDD:473070	1/4 (25%)
		COG4076	154..341	CDD:443253	79/193 (41%)
HMT1	NP_009590.1	COG4076	33..>207	CDD:443253	75/187 (40%)